Novel Cognitive Treatment Targets for Epidiolex in Sturge- Weber Syndrome

Status Completed

Clinical Trial Summary

The purpose of this study is to better understand the utility of cannabidiol (CBD/ Epidiolex) for improving the treatment of cognitive impairments in Sturge-Weber syndrome (SWS).

Clinical Trial Description

The investigators hope to gain an understanding of the utility of pharmaceutical grade CBD used for the treatment of cognitive impairments in SWS in this open-label study. Anecdotal evidence from a phase I trial investigating the use of CBD for medically refractory seizures suggests CBD may also have a beneficial effect on cognition, mood, and behavior. The investigators hypothesize that CBD/ Epidiolex will improve SWS brain function resulting in improved cognitive function, social interactions, mood, motor function and behavior, as well as reduced migraines. This is an open-label prospective oral drug trial of Epidiolex in 10 subjects. Assessments will be done at baseline and repeated after 6 months on study drug. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04447846
Study type	Interventional
Source	Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Contact
Status	Completed
Phase	Phase 2
Start date	October 14, 2019
Completion date	December 9, 2022

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See also
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