Sturge - Weber Syndrome (SWS) Clinical Trial
Official title:
Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)
| NCT number | NCT00610402 |
| Other study ID # | 20065691 |
| Secondary ID | |
| Status | Completed |
| Phase | |
| First received | |
| Last updated | |
| Start date | July 2007 |
| Est. completion date | June 2008 |
| Verified date | October 2022 |
| Source | University of California, Irvine |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
Sturge-Weber Syndrome (SWS) is a neurological disorder characterized at birth by seizures and a large port-wine stain birthmark on the forehead and upper eyelid of one side of the face. SWS is also accompanied by an increased pressure within the eye (glaucoma) which can develop very early in life. Glaucoma represents a group of ocular disorders that are characterized by the loss of retinal ganglion cells and their axons, damage to the optic nerve, and gradual loss of visual field. Recently, several studies provided evidence that there is a potential role of the immune system in the pathogenesis of glaucoma. These findings suggest that there might be changes in systemic humoral immunity possibly underlying the optic neuropathy in at least some glaucoma patients.
| Status | Completed |
| Enrollment | 57 |
| Est. completion date | June 2008 |
| Est. primary completion date | July 2007 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | N/A and older |
| Eligibility | Inclusion Criteria: - Male and female volunteers with SWS of all ages Exclusion Criteria: - Volunteers without SWS |
| Country | Name | City | State |
|---|---|---|---|
| United States | Beckman Laser Institute Medical clinic | Irvine | California |
| Lead Sponsor | Collaborator |
|---|---|
| University of California, Irvine | Mainz University |
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