Physiological Responses in Tobacco Chippers

Stress Clinical Trial

Official title:

Physiological Responses in Tobacco Chippers (Non Nicotine-dependent Light Smokers)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01237834
• Other study ID #: IRB6698
• Status: Completed
• Phase: N/A
• First received: November 9, 2010
• Last updated: October 28, 2014
• Start date: November 2010
• Est. completion date: January 2013

Study information

• Verified date: October 2014
• Source: Oregon Health and Science University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

This study will analyze a series of biological and behavioral markers in different populations of smokers. The study groups will differ in their cigarette consumption and level of nicotine dependence. This analysis will help to identify factors that might be important for smoking behavior and nicotine addiction. The results from this study will contribute to improve campaigns for smoking prevention and treatments for smoking cessation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 178
• Est. completion date: January 2013
• Est. primary completion date: January 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 25 Years to 55 Years

Eligibility

Inclusion Criteria:

• healthy adults

• age 25-55

Exclusion Criteria:

• alcohol or drug addiction

• unstable significant medical problems

• neurologic disease

• medications known to affect CNS function or impact physiologic parameters measured in the study

• significant visual impairment

• breath carbon monoxide (BCO) level of less than 10 ppm for smokers

• breath carbon monoxide (BCO) level of more than 5 ppm for non-smokers

• for heavy regular smokers: erratic smoking history (i.e. they must have smoked an average of 15 cigarettes daily for at least one year)

Study Design

Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Smoking
• Stress

Locations

Country	Name	City	State
United States	Oregon Health and Science University	Portland	Oregon

Sponsors (1)

Lead Sponsor	Collaborator
Oregon Health and Science University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Electroencephalography	Electroencephalography will be measured during performance on a hard cognitive task.	Changes from baseline during a hard cognitive task	No
Secondary	Salivary cortisol	Salivary cortisol will be measured at baseline, during a hard cognitive task and 30 minutes after the cognitive task.	Changes from baseline during performance on a hard cognitive task	No