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Contribution of L-Tyrosine to Human Decision Making in Stressful Situations — TYRO-STRESS  

Stress, Psychological Clinical Trial

Official title:
Contribution of L-Tyrosine to Human Decision Making in Stressful Situations

Clinical Trial Summary

L-tyrosine is a chemical precursor of dopamine. Under specific conditions, tyrosine administration can increase brain dopamine levels and therefore several studies have explored whether tyrosine supplementation can have a beneficial effect on cognitive and behavioural performance that is dependent on dopaminergic function. However, the effects of tyrosine supplementation are mixed: some studies show positive effects while others do not. Stress leads to an increase in dopaminergic activity and turnover in the brain, resulting in a decrease in brain dopamine levels. We propose to study the contribution of tyrosine to decision making and more particularly to the processes of response selection (mediated by the prefrontal cortex and under the influence of the dopaminergic system) in stressful situations.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04518254
Study type Interventional
Source Direction Centrale du Service de Santé des Armées
Contact
Status Completed
Phase N/A
Start date November 18, 2021
Completion date April 7, 2022
View Details
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