Stress Disorders Clinical Trial
Official title:
Effects of an Alternative Treatment for Military Sexual Trauma on PTSD Symptoms, Neurosteroids and Brain Function
Our specific aims are:
1. To examine the efficacy of GIFT in improving MST-related clinical outcomes in women
veterans
2. To examine the effects of GIFT on fronto-limbic brain function and
3. To examine the effects of GIFT on levels of neuroactive steroid associated with PTSD.
Guided imagery is a complementary and alternative treatment (CAM) modality. This directed
meditation technique uses healing imagery to promote recovery in a variety of illnesses,
including cancer, heart disease and, more recently, posttraumatic stress disorder (PTSD).
PTSD is a severe and disabling anxiety disorder. It is among the most common mental
disorders, affecting 10% of women in the United States during their lifetime. Sexual assault
is the most common cause of PTSD. Similarly, military sexual trauma (MST) is disturbingly
common among women in the armed forces. At least 20% of women veterans using VA services
report a history of sexual assault. Unfortunately, high rates of MST-related PTSD are
anticipated among women currently deployed to Iraq and Afghanistan.
To address this issue, we will evaluate a guided imagery intervention for women veterans who
have MST-related PTSD. We will evaluate the efficacy of Guided Imagery for Trauma (GIFT) in
decreasing PTSD symptoms. Using brain-imaging techniques, this research will examine the
effects of GIFT on brain function in the areas associated with PTSD. We will also examine
the effects of GIFT on neurosteroids, which are candidate modulators of PTSD symptoms, and
may also represent novel targets for therapeutic intervention.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Primary Purpose: Treatment
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