Neurophysiological and Neuropsychological Evalution in Healthcare Workers

Stress Disorders, Post-Traumatic Clinical Trial

— EEGCOV  

Official title:

Neurophysiological and Neuropsychological Evalution in Healthcare Workers of Stress Condition

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06368999
• Other study ID #: EEGCOV
• Status: Completed
• Phase: N/A
• Start date: May 27, 2020
• Est. completion date: January 9, 2021

Study information

• Verified date: March 2024
• Source: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this observational study is to compare in participant population the effect of stress condition on cerebral EEG activity Participants will do an 8 minutes EEG registration. Researchers will compare EEG activity of heathcare workers.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: January 9, 2021
• Est. primary completion date: December 21, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 21 Years and older

Eligibility

Inclusion Criteria:

• healthcare workers

Exclusion Criteria:

• neurological disorders

Related Conditions & MeSH terms

• Stress Disorders, Post-Traumatic

Intervention

Diagnostic Test:
• EEG
registration of 8 minutes of EEG

Locations

Country	Name	City	State
Italy	Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico	Milan

Sponsors (1)

Lead Sponsor	Collaborator
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Country where clinical trial is conducted

Italy, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	EEG activity	The subjects were instrumented with 19 bridge silver and silver chloride electrodes fitted on a plastic prewired head cap and placed on the scalp according to the 10-20 system (namely: Fp1, Fp2, F3, F4, F7, F8, Fz, C3, C4, Cz, P3, P4, Pz, T3, T4, T5, T6, O1, and O2), with an electroconductive paste applied between the electrodes and the skin to guarantee optimal connection The signals were recorded with a 512 Hz sampling frequency and filtered by an offline first order zero-phase Butterworth band-pass filter, with cutoff frequencies set, respectively, at 1.6 and 70 Hz to remove frequencies outside the range of interest. After this pre-processing, the main EEG rhythms and dominant frequencies were extracted by spectral and connectivity analyses. Delta (1.6-4 Hz), theta (4-8 Hz), alpha (8-13 Hz), beta (13-30 Hz), gamma1 (30-50 Hz), and gamma2 (50-70 Hz) frequency bands were considered.	immediately after the outbreak of the pandemic (first session) and almost 6 months later (second session).