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Stress Disorders, Post-Traumatic clinical trials

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NCT ID: NCT05280964 Completed - Burnout Clinical Trials

Better Together: an Online Physician Coaching Program for Medical Trainees

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

This is a single-institution randomized controlled trial. 101 female residents were recurited from the University of Colorado School of Medicine. They enrolled beginning in January 2021 and participated in the coaching program for 6 months via a web-based system. Participants were randomized into either the intervention or wait-list control arm. Participants in the intervention arm began the 6-month coaching program in January, 2021. Participants in the wait-list control arm have received no additional resources from the Better Together program between January and June 2021. The wait-list control group was invited to begin the 6-month coaching program in July 2021. In December 2021, participants from both the intervention and wait-list control groups will be invited to complete a 2nd post survey (identical to the post-survey from June 2021). There will be no incentive for completion of the 2nd post survey. Finally, the longitudinal effect of the program will be assessed by offering the same survey measuring wellbeing via various indices to the intervention arm at 6 months (1/2022), 12 months (7/2022) and 18 months (1/2023) after their intervention. Participation in this survey will be completely voluntary and not incentivized/compensated.

NCT ID: NCT05261230 Completed - Clinical trials for Post Traumatic Stress Disorder

Vedic Counselling for Women Victims of Domestic Abuse

Start date: October 21, 2021
Phase: N/A
Study type: Interventional

The Vedic Counselling is the whole person approach, system of total life style counselling based on 'Vedic Laws of right living, right actions, right relationship and right awareness'.Vedic Counselling was developed as trauma focused therapy for this study to treat female victims of domestic abuse.

NCT ID: NCT05226481 Completed - PTSD Clinical Trials

Investigating the Effect of Evidence-based Treatment for Post-traumatic Stress Disorder Among Youth

Start date: January 1, 2018
Phase:
Study type: Observational

Trauma-focused cognitive-behavioral therapy (TF-CBT) is an evidence-based practice (EBP) for the treatment of posttraumatic stress disorder (PTSD) and posttraumatic stress symptoms (PTSS) among children and adolescents. In the current study, data were collected from youth receiving TF-CBT in specialized child and adolescent mental health services (CAMHS) and their caregivers in 2018-2021.

NCT ID: NCT05212714 Completed - Clinical trials for Stress Disorders, Post-Traumatic

taVNS to Reduce PTSD Symptoms in WTC Responders

taVNS
Start date: March 31, 2022
Phase: N/A
Study type: Interventional

This study seeks to conduct a randomized, double-blind pilot study, to determine whether the Transcutaneous Auricular Vagus Nerve Stimulation and study procedure are feasible and acceptable for use with World Trade Center responders with Post Traumatic Stress Disorder.

NCT ID: NCT05207462 Completed - Clinical trials for Post Traumatic Stress Disorder

A Feasibility Study of Intensive Treatment With Prolonged Exposure

Start date: January 24, 2022
Phase: N/A
Study type: Interventional

The primary objective with this study is to investigate the feasibility and acceptability of intensive treatment with prolonged exposure (I-PE) in regular Swedish psychiatric care. The secondary objective is to investigate preliminary effects of i-PE in terms of reducing symptoms of post-traumatic stress, depression and increase quality of life.

NCT ID: NCT05207436 Completed - Clinical trials for Post Traumatic Stress Disorder

Brief Cognitive Behavioral Conjoint Therapy for PTSD With Adjunctive Intranasal Oxytocin

CBCT+OT
Start date: January 17, 2022
Phase: Phase 2
Study type: Interventional

In 2019 VA mandated that all Veterans seeking mental health care have access to flexible family mental health services in VA (VHA directive 1163.04). This study aims to respond to this mandate by further improving an evidence-based PTSD treatment designed to decrease PTSD symptoms and improve relationship satisfaction for Veterans and their romantic partners. Brief Cognitive-Behavioral Conjoint Therapy (B-CBCT), an 8-session dyadic psychotherapy for PTSD, has been found to significantly reduce PTSD symptoms, but the effects of B-CBCT on relationship satisfaction are less reliable and robust. Pharmacological augmentation of psychotherapy utilizing intranasal oxytocin, a neurohormone that influences mechanisms of trauma recovery and social behavior, may help improve relationship satisfaction outcomes. If successful, the proposed study will advance knowledge of strategies for improving Veterans' quality of life by improving their intimate relationships along with PTSD symptoms.

NCT ID: NCT05206734 Completed - Schizophrenia Clinical Trials

Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health

Start date: January 5, 2022
Phase:
Study type: Observational

This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the risk of mental health conditions in children, adolescents and young adults with Inflammatory Bowel Disease, compared to those without Inflammatory Bowel Disease. The study will also compare the impacts on quality-of-life outcomes and use of healthcare services between people with Inflammatory Bowel Disease with and without mental health conditions.

NCT ID: NCT05195684 Completed - Clinical trials for Posttraumatic Stress Disorder

MGH Trauma-related Nightmares SDI Study

NM
Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Interested individuals will first complete a telephone screening followed by a series of structured clinical interviews to diagnose PTSD and comorbid psychiatric disorders, confirm initial inclusion criteria, rule out exclusion criteria and create an audio-recorded account of their index trauma. Participants passing screenings will then complete 2 weeks of at-home sleep and nightmare diaries and time-stamped audio-recorded reports of dream content upon awakening from any nightmare. They will also wear a wrist actigraph throughout this period, complete 2 nights of ambulatory PSG, and complete on-line questionnaires. Nightmare data will be examined for frequency and thematic similarity of nightmares to a participant's reported index trauma. Participants' nightmare and index trauma reports will be audio-recorded for use as scripts during SDI. The participant will then undergo two SDI sessions on a single day, one with a nightmare script and one with an index-trauma script, during which they will wear the NINscan. Sessions will be separated by 1 hour and counterbalanced across participants for script order.

NCT ID: NCT05186844 Completed - Clinical trials for Posttraumatic Stress Disorder

Posttraumatic Stress Disorder in Parents and Children After Discharge From the Pediatric Intensive Care Unit

PTSD
Start date: January 1, 2019
Phase:
Study type: Observational [Patient Registry]

Background: If disorders that occur immediately after a trauma are not treated, they may become chronic and turn into severe health problems. Objectives: This study was conducted with children who had spent time in an intensive care unit and their parents to examine the development of posttraumatic stress disorder (PTSD) in both children and parents. Methods: The study was a cross-sectional study. A total of 110 children, 98 mothers and 80 fathers were included in the study.

NCT ID: NCT05178316 Completed - Clinical trials for Post Traumatic Stress Disorder

A Study of JZP150 in Adults With Posttraumatic Stress Disorder

Start date: December 29, 2021
Phase: Phase 2
Study type: Interventional

This is a 12-week, double-blind, placebo-controlled, randomized, parallel-group, multicenter study of the safety and efficacy of JZP150 in the treatment of adult participants with post-traumatic stress disorder (PTSD).