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Stomatognathic Diseases clinical trials

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NCT ID: NCT06467890 Not yet recruiting - Knowledge Clinical Trials

Knowledge of Vital Pulp Therapy in Permanent Teeth After Educational Programme: A Before and After Study

Start date: September 1, 2024
Phase:
Study type: Observational

evaluating the extent of knowledge of vital pulp therapy in permanent dentition among a group of dental interns in Egypt after educational programme.

NCT ID: NCT06380296 Not yet recruiting - Clinical trials for Pulp Disease, Dental

Outcomes of NeoMTA and NeoPUTTY Pulpotomies in Primary Molars

Start date: April 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the outcomes of different medications used for pulpotomies (baby root canal) in children. The main question it aims to answer is: • what are the long-term clinical and radiographic success of pulpotomies in baby teeth using two different medications (NeoMTA and NeoPUTTY) over a 24-month follow-up period? Healthy children aged between 3 and 10 years undergoing dental treatment under general anesthesia who have deep caries lesions approximating or reaching the nerve will be invited to participate in this study. Pulpotomies (baby root canal) will be performed by trained dentists following a protocol. Children will receive pulpotomies either with NeoMTA or NeoPUTTY, two medications indicated for the procedure. Participants will be asked to come for an appointment at 1, 6, 12 and 24 months after the procedure. Researcher will compare the clinical and radiographic performance of pulpotomies (baby root canal) done with both medications.

NCT ID: NCT06348953 Not yet recruiting - Dental Caries Clinical Trials

Bioactive Versus Non-Bioactive Restorative System in Deep Carious Molars

Start date: April 2024
Phase: N/A
Study type: Interventional

This research study delves into the effectiveness of bioactive and non-bioactive restorative systems in deep carious permanent molars treated with selective caries removal. Selective caries removal techniques aim to preserve as much healthy tooth structure as possible while effectively eliminating carious tissue. The study investigates how the choice of restorative material influences the outcomes of selective caries removal procedures in deep carious lesions. By assessing factors such as restoration integrity, pulpal response, and long-term success rates, the research seeks to provide evidence-based insights into the comparative performance of bioactive and non-bioactive restorative systems in this clinical context.

NCT ID: NCT06252935 Not yet recruiting - Dental Diseases Clinical Trials

Effectiveness and Safety of Collagen Membrane (FormaAid®) in the Treatment of Periodontal Regeneration

Start date: March 12, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate clinically and radiographically effectiveness and products safety of the collagen membrane (FormaAid®) in the treatment of periodontal regeneration using guided tissue regeneration (GTR) performed by the trained periodontists. The main question it aims to answer are: - The difference of periodontal status: clinical attachment level (CAL), periodontal pocket depth (PPD), gingival recession (GR), gingival Index (GI) and plaque index (PI). - The difference of intrabony defect height. - The difference of gingival tissue thickness and gingival tissue volume. - The incidences of safety indicators. Participants will be randomized into either experiment group or control group, undergo guided tissue regeneration (GTR) surgery at week 1, and re-visited on week 3, 5, 13 and 27 after the GTR surgery. Researchers will compare if the test product is non-inferior to Bio-Gide.

NCT ID: NCT06170775 Not yet recruiting - Clinical trials for Pulp Disease, Dental

Sodiumhexametaphosphate as Pulp Capping Material for Primary Teeth

Start date: December 20, 2023
Phase: N/A
Study type: Interventional

Sodiumhexametaphosphate will be tested as pulp capping material in comparison to MTA for primary teeth pulp therapy

NCT ID: NCT06170762 Not yet recruiting - Clinical trials for Pulp Disease, Dental

Sodiumhexametaphosphate Versus MTA as Pulp Capping Material for Immature Permanent Teeth

Start date: December 20, 2023
Phase: N/A
Study type: Interventional

Sodiumhexametaphosphate will be used as capping material for dental pulp of immature permanent teeth

NCT ID: NCT06081868 Not yet recruiting - Dental Caries Clinical Trials

RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda

Start date: September 1, 2024
Phase: N/A
Study type: Interventional

Dental caries represents a challenge for Oral Health Services in several African Countries, like Uganda. Few studies have been reported the burden of oral health, its prevention and non-operative treatment among school children in African countries. Aim: To assess the prevalence and risk factors of dental caries and the effectiveness of strategies to prevent and treat dental caries using a non-operative approach among children in Gulu Municipality, Uganda. Methods: The proposal RCT is structured in three phases: 1. A descriptive cross-sectional survey to collect oral data among 610 school children selected using a multistage cluster sampling; 2. A randomized unblinded two-arm trial to assess the difference in the treatment/prevention of dental caries using non-operative means among school children in the Ugandian Gulu municipality; and 3. A comparison of oral health conditions between a group of children who will be given dental cleaning tools and followed up over time versus a control group. The oral health status of the participants will be assessed according to WHO and ICDAS guidelines. Stata 14.0. will be used for analysis; descriptive statistics will be carried out to analyze continuous and categorical variables and chi-square test as well as independent tests for bivariate analysis and modified poisson regression. In addition, the factors associated with dental caries will be determined by linear regression models using a statistical significance level of 5% (α = 0.05). Discussion: This trial will be the first trial conducted in Uganda assessing a school-based caries prevention programme using the WHO and ICDAS standardized international guidelines. The findings obtained will increase knowledge on oral health in Uganda school children and the effectiveness of community-based caries prevention programme in this population.

NCT ID: NCT05981352 Not yet recruiting - Clinical trials for Pulp Disease, Dental

Evaluation of Different Materials in Pulpotomy of Primary Molars

Start date: October 2023
Phase: N/A
Study type: Interventional

The aim of the current study is to evaluate and compare clinical and radiographic success and antibacterial effect of Hyaluronic Acid and Amniotic membrane pulpotomy in primary molars in comparison with MTA pulpotomy (Randomized Clinical Trial and In Vitro Study).

NCT ID: NCT05839548 Not yet recruiting - Clinical trials for Dental Caries in Children

Articaine Efficacy and Safety for 3 Years Old Children

Start date: June 1, 2023
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to determine the local anesthetic efficacy and safety of 4% Articaine compared 2% Mepivicaine in 3 years old children, by using infiltration technique for primary teeth that required restorative, pulp therapy, or dental extraction procedure, as assessed by measuring the pain experience during injection and treatment procedures, child's behavior during the procedure, and postoperative complications.

NCT ID: NCT05624489 Not yet recruiting - Dental Diseases Clinical Trials

Micro-Randomized Trial to Optimize Digital Oral Health Behavior Change Interventions

DCBI
Start date: February 2023
Phase: N/A
Study type: Interventional

The study will involve a 10-week Micro-Randomized Trial (MRT) to inform the delivery of prompts (via mobile app push notifications) designed to facilitate adherence to an ideal tooth brushing protocol (2x2x4; 2 sessions daily, 2 minutes per session, all 4 quadrants).