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Stomatognathic Diseases clinical trials

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NCT ID: NCT05371535 Not yet recruiting - Dental Diseases Clinical Trials

A Clinical Trial to Evaluate the Safety and Effectiveness of MatrixOssTM Bone Graft

Start date: May 30, 2022
Phase: N/A
Study type: Interventional

The objective of this clinical trial is to evaluate the efficacy and safety of MatrixOssTM Bone Graft in bone defect repair caused by tooth extraction.

NCT ID: NCT05021874 Not yet recruiting - Pain Clinical Trials

The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures.

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The study will determinate influence of four selected physiotherapeutic procedures on the pain intensity and the range of mandibular mobility in patients with myofascial disorders in the SS.

NCT ID: NCT04946617 Not yet recruiting - Clinical trials for Periodontal Diseases

Chlorhexidine and Essential Oil Mouthwashes on Human Beta-Defensin 2 (hbD2) and Kathelicidin (LL-37) Saliva Levels

hbD2
Start date: July 20, 2021
Phase:
Study type: Observational [Patient Registry]

Recent studies have shown that while mouthwashes exhibit antimicrobial properties against bacteria and their products, at the same time showing the cytotoxic effect on living cells in the mouth.29 To the best of our knowledge, there is no information about the toxicity effect of these two mouthwashes, which are highly preferred, on antimicrobial peptides secreted from the oral epithelium. Therefore, our aim in this study is to evaluate the effect of chlorhexidine and essential oil mouthwash on hBD2 and LL-37 in saliva.

NCT ID: NCT04650113 Not yet recruiting - Clinical trials for Pulp Disease, Dental

Clinical and Radiographic Assessment of Partial and Complete Pulpotomy in Primary Molars Using MTA

Start date: January 20, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

that's comparison between partial and complete pulpotomy techniques in primary teeth

NCT ID: NCT03368391 Not yet recruiting - Clinical trials for Pulp Disease, Dental

: Pulpal Blood Flow With the Use of Intra-nasal Anesthetic

Start date: January 3, 2018
Phase: Phase 4
Study type: Interventional

Anesthetics with vasoconstrictors decrease pulpal blood flow but the impact of intranasal local anesthetics on blood flow is unknown. This blinded, randomized crossover clinical trial will compare the effects of different local anesthetics on anterior teeth in healthy volunteers. On separate study visits patients will receive either traditional injections or intranasal administration of the following solutions: 2% lidocaine with 1:100,000 epi, 3% mepivacaine, tetracaine HCl and oxymetazoline HCl, or saline. The following variables will be assessed: pulpal blood flow, pulpal sensibility, pain on administration, and adverse outcomes.

NCT ID: NCT03103685 Not yet recruiting - Dental Diseases Clinical Trials

Continue vs. Stop P2Y12 Inhibitor on Bleeding in Patient Receiving DAPT Undergoing Dental Procedure.

Start date: May 1, 2017
Phase: Phase 4
Study type: Interventional

This is a prospective randomized open-label blinded endpoint (PROBE) The study will be conducted in Maharaj Nakorn Chiang Mai hospital. The patients with dual-antipletlet who need dental procedure between Febuary 2017 until Febuary 2018 will be included in the study. Baseline characteristics of the enrolled patients including bleeding complication will be collected in each patient. To compare rate of significant bleeding from dental procedure between patient who need two antiplatelet and who stop P2Y12 inhibitors before procedure.

NCT ID: NCT03068962 Not yet recruiting - Non-smoking Clinical Trials

Examination of the Distribution of Nitrate Reducing Bacteria in the Human Oral Cavity

REBOC
Start date: March 2017
Phase: N/A
Study type: Interventional

Dietary nitrate have been shown to have health benefits including lowering blood pressure (Hobbs et al, 2012), improving endothelial function and inhibiting platelet aggregation in healthy humans (Lidder & Webb, 2013). The main sources of dietary nitrate in the human diet are vegetables such as beetroot. Nitrates are converted to nitrites then nitric oxide (NO), following their reduction by commensal oral bacteria and those residing in the gastrointestinal tract (Hord, Tang, & Bryan, 2009; Lidder & Webb, 2013). A recent study has shown following elimination of oral bacteria by the use of a chlorhexidine based antiseptic mouthwash, the conversion of nitrate to nitrite is prevented and this is accompanied by a statistically significant increase in blood pressure in normotensive subjects (Kapil et al., 2013). To date, very few studies have investigated the potential role of these oral bacteria in control of blood pressure and if there are any inter and intra-individual differences in bacterial composition.