Clinical Trials Logo
  1. Home
  2. Stoma Colostomy
  3. NCT05245565

Effects of Modified Precision Functional Sphincter-Preserving Surgery (PPS) on Ultralow Rectal Cancer

Rectum Cancer Clinical Trial

Official title:
Effects of Modified Precision Functional Sphincter-Preserving Surgery (PPS) on Ultralow Rectal Cancer: A Multicenter Prospective Cohort Study

Clinical Trial Summary

RATIONALE: Colorectal cancer is one of the most common cancers. However, approaches to minimize surgical trauma, preserve anal function, avoid abdominal stoma, and improve quality of life for patients with ultralow rectal cancers were limited. Thus, new technologies are urgently needed to improve the anal preservation rate, reduce the incidence of anastomotic leakage and improve postoperative anal function in patients with ultralow rectal cancer. PURPOSE: This one-arm multicenter prospective cohort study aims to collect the data of patients with ultralow rectal cancer who undergo sphincter-preserving surgeries, including modified PPS and conventional surgeries, then compare the effects of different operations on clinical outcomes and to see the efficacy and safety of modified PPS surgery when compared with conventional procedures in the treatment of ultralow rectal cancer.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05245565
Study type Observational
Source Shanghai 10th People's Hospital
Contact Cheng-Le Zhuang, MD, PhD
Phone +86-19921618250
Email zhuangchengle@tongji.edu.cn
Status Recruiting
Phase
Start date May 1, 2021
Completion date May 1, 2026
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05400122 - Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer Phase 1
Completed NCT00409994 - Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer Phase 1/Phase 2
Completed NCT04371198 - Patient-Derived Organoids for Rectal Cancer N/A
Recruiting NCT04916990 - Improving Care for Rural Patients With Solid Tumors N/A
Active, not recruiting NCT05305820 - Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal Malignancy N/A
Recruiting NCT03699761 - The Role of Pelvic Peritonization in Laparoscopic or Robotic Low Anterior Resection N/A
Recruiting NCT04907643 - Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes N/A
Completed NCT03843957 - Effectiveness and Implementation of mPATH-CRC N/A
Completed NCT02423226 - Computed Tomography-guided Brachytherapy Plus Chemotherapy for Locally Recurrent Rectum Cancer Phase 2
Completed NCT00379743 - Partnership for Healthy Seniors N/A
Completed NCT00509444 - Cancer Prevention and Treatment Among African American Older Adults: Treatment Trial Phase 3
Recruiting NCT06116019 - Online Adaptive Radiotherapy Using a Novel Linear Accelerator (ETHOS)
Not yet recruiting NCT06066931 - Reconstruction of the Pelvic Floor and Perineal Wound After Rectal ELAPE N/A
Recruiting NCT02738359 - Efficacy of Colonoscopy, Colon Capsule and Fecal Immunological Test for Colorectal Cancer Screening
Completed NCT02997553 - Fluorescence for Sentinel Lymph Node Identification in Cancer Surgery Phase 3
Active, not recruiting NCT02458664 - BASE HSP110 : A New Therapeutic Target and a New Marker for Prognosis of Type MSI Colorectal Cancer N/A
Withdrawn NCT03257332 - Determining Early Development of Faecal Incontinence and Anorectal Muscle Function After Surgery for Rectal Cancer.
Recruiting NCT05715255 - Adaptive Symptom Self-Management Immunotherapy Study N/A
Completed NCT02641691 - Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum Phase 2
Recruiting NCT04405206 - Total Neoadjuvant Therapy Followed by 'Watch and Wait' Approach or Organ Preservation for Low-risk Rectal Cancer