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Sternal Wound Infection clinical trials

View clinical trials related to Sternal Wound Infection.

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NCT ID: NCT04592328 Completed - Clinical trials for Surgical Site Infection

Sternal Wound and Aortic Graft (SWAG), an Observational Cohort Study.

SWAG
Start date: October 12, 2020
Phase:
Study type: Observational

The aim of this study is to systematically explore the perioperative presence of P acnes in all layers of sternal wound incision as well as contamination of graft material and prosthetic valves during primary operation. Secondly, to compare if different regimes of antibiotics affects the bacterial growth. Cultures will be taken from the skin, subcutaneous, and from the implanted valve prostheses with a rayon swab.Graft and Felt material will, after being pressed subcutaneous for 15 sec, placed into prepared sterile bottles containing broth for aerobe and anaerobe cultures. Surgical gloves will be cultured.

NCT ID: NCT00819286 Completed - Pain Clinical Trials

Evaluation of Primary Plating in Sternotomy Patients for Osteosynthesis and Pain

RESTORE
Start date: November 2008
Phase: N/A
Study type: Interventional

The goal of this study is to evaluate sternal osteosynthesis, chest wall pain and return to normal activity in open heart surgery patients who had their breast bone closed either with wires or plates.

NCT ID: NCT00638014 Completed - Mediastinitis Clinical Trials

Rapid Sternal Closure System (TALON)

TALON
Start date: March 2008
Phase: Phase 4
Study type: Interventional

The primary objective is to establish if the Rapid Sternal Closure System (RSCS) improves early postoperative recovery as manifested by decreased pain and improved pulmonary function. Secondary objectives include evaluation of Rapid Sternal Closure System with regard to SWCs (surgical wound complication defined as surgically treated sternal wound infection and sternal instability/non-union) as outlined in the protocol. For a given study endpoint, the null hypothesis will be no difference between the Rapid Sternal Closure System group and the control group. The alternative hypothesis will be a difference between 2 groups. The statistical objective of this study is to reject the null hypothesis in favor of the alternative hypothesis.

NCT ID: NCT00600483 Completed - Cardiac Surgery Clinical Trials

Safety and Efficacy of an Antibiotic Implant in Cardiac Surgical Subjects at Higher Risk for Sternal Wound Infection

Start date: December 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether the gentamicin-collagen sponge is safe and effective in preventing sternal wound infections in patients undergoing cardiac surgery who are at a greater risk of developing sternal wound infections.