Sterility Clinical Trial
Official title:
Does the Operator Performing the Embryo Transfer Significantly Influence the Cycle Outcome: A Retrospective Evaluation of Humanitas Fertility Center's Experience
Several studies had analyzed the correlation between embryo transfer operator experience and
implantation, clinical pregnancy, abortion and delivery rate.
The aim of the present study is determining if the probabilities of embryo implantation and
pregnancy are associated to the operator performing the embryo transfer.
This study allows following more than 30 different operators in a global period of 20 years
with almost 20,000 procedures.
Several studies had analyzed the correlation between embryo transfer operator experience and
implantation, clinical pregnancy, abortion and delivery rate. Until now, the evidences are
mixed and inconclusive.
The aim of the present study is determining if the probabilities of embryo implantation and
pregnancy are associated to the operator performing the embryo transfer.
The database includes all the fresh embryo transfers, performed between January 1997 and
December 2016 at Humanitas Fertility Center after IVF-ICSI cycles. Only embryo transfers
performed by the surgeon on duty for that day ("Gynecologist of the Day") will be included.
Secondary end point is to evaluate if it is possible to draw a learning curve for transfer in
terms of pregnancies for the different surgeons.
The strength of this study relies on the completeness of the preoperative factors and follow
up and on the vastest dataset in literature that can permit to correct for multiple
confounders and analyze a wide group of outcomes.
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