| Eligibility |
Inclusion Criteria Recipient:
- Patient with sterility for absolute uterine factor (malformation or previous surgery
for benign processes).
- Age <40 years.
- Absence of pathology that contraindicates a complex surgical process,
immunosuppression or gestation.
- Positive results to the IVF cycle prior to the surgery, obtaining quality embryos.
- Acceptance to participate in the study signing the informed consent.
Exclusion Criteria Recipient:
- Medical or surgical pathology that contraindicates a complex pelvic surgical
procedure.
- Medical conditions that contraindicate, may aggravate or complicate the
immunosuppressor treatment, such as neoplastic or preneoplasic diseases, chronic
infectious diseases, autoimmune diseases, renal or liver failure.
- Medical or surgical pathology that contraindicates pregnancy.
- Anatomic alterations or vascular pathology that might difficult the vascular
anastomosis: severe endometriosis, pelvic kidney, severe adherence syndrome or others.
- Uncontrolled psychopathology.
Inclusion Criteria donor:
- Age <65 years.
- First- or second-degree relatives.
- Completed reproductive desire.
- History of previous pregnancies and births.
- Absence of associated pathology that contraindicates prolonged and complex
laparoscopic surgery (pneumopathies, heart disease, morbid obesity, …).
- Acceptance to participate in the study signing the informed consent
Exclusion Criteria donor:
- Potential future pregnancy desire.
- Surgery for the treatment of gender identity disorder.
- Infections: HIV or risk group, HBV-DNA and / or HBsAg positive, positive HCV, active
bacterial sepsis, infections with multi-resistant bacteria, active tuberculosis or
incomplete treatment of the same, Chagas disease, untreated active viral infections.
- Active malignant cancer of any location, except skin basal cell carcinoma. Treated
cancer without current evidence of illness but with a follow-up of less than 5 years.
- Benign pelvic pathology: uterine fibroids, uterine malformations, severe
endometriosis, severe adherence syndrome.
- Vascular pathology: malformations, atheromatosis, hypertensive or diabetic
vasculopathy, connective tissue disease with vascular involvement.
- Premalignant pelvic pathology: pre-invasive cervical and/or vaginal, endometrial
hyperplasia.
- BRCA mutation carriers or genes related to Lynch syndrome.
- History of implantation failure or multiple abortions of unknown cause.
- Contraindications for the surgical procedure of donation through laparoscopy: diabetes
mellitus, liver disease, nephropathy, heart disease, pneumopathy, morbid obesity or
high-risk cardiovascular factors.
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