Management of Non Convulsive Status Epilepticus

Status Epilepticus Clinical Trial

Official title:

Management of Non Convulsive Status Epilepticus

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03245099
• Other study ID #: MONCSE
• Status: Not yet recruiting
• Phase: N/A
• First received: August 4, 2017
• Last updated: August 7, 2017
• Start date: December 2017
• Est. completion date: April 2019

Study information

• Verified date: August 2017
• Source: Assiut University
• Contact: Gamal Askar, MD
• Phone: 01111686162
• Email: Gamal.askar[@]med.au.edu.eg
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Non convulsive status epilepticus is a persistent change in behavioural and or mental process from baseline associated with continuous epileptiform activity in electroencephalograph,it occur in about 50 percent in patients with coma and convulsions and in 8-13 percent in intensive care unit patients

Description:

Early recognition and treatment of non convulsive status epilepticus are essential to optimize response to treatment and to prevent neurological sequelae, over diagnosis and aggressive use of anticonvulsants can contribute to morbidity and mortality.It displays great diversity in response to anticonvulsants,therefore treatment in intensive care units is required for selected cases .The aetiology and clinical forms are strong predictors for the overall prognosis.Treatment is poorly understood and follows the standard regimen for convulsive status epilepticus

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 100
• Est. completion date: April 2019
• Est. primary completion date: December 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 12 Months to 18 Years

Eligibility

Inclusion Criteria:

• patients who have generalized tonic colonic convulsions and prolonged post ictal state more than 30 minutes

• patients presented with un explained psychic or speech disorder

• patients presented with stupor or confusion

• Patients presented with un explained coma

Exclusion Criteria:

• patients with progressive neurological disease

• Patients with severe cerebral anoxia

• Patients with liver or hepatic impairment

Related Conditions & MeSH terms

• Status Epilepticus

Intervention

Other:
• cross sectional
Electroencephalograph will be done to all patients who fulfill the inclusion criteria to detect presence of electrical discharge with in the brain.Complete blood count ,liver function test ,kidney function test ,blood glucose level and serum electrolytes will be done to selected cases according to the clinical presentation

Locations

Country	Name	City	State
Egypt	AssiutU	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of cured patients	Number of cured patients	An average of 1 year