Sunitinib Malate Related Fatigue in Patients With Metastatic Kidney Cancer

Status Terminated

Clinical Trial Summary

The purpose of this research study is to determine how sunitinib (sunitinib malate) causes fatigue. Patients will be asked to complete a brief questionnaire (survey) to rate their levels of fatigue every two weeks while they are participating in this research study. The questionnaire takes approximately 10-15 minutes to complete and is 9 questions. A series of physical measurements for fatigue will be performed before the first dose of sunitinib and again (4) weeks later to see if there are any changes in physical level of fatigues

Clinical Trial Description

PRIMARY OBJECTIVES:

I. To determine the mechanisms associated with sunitinib related fatigue by recording EMG signals during a submaximal elbow contraction, twitch force and TMS prior to and at the end of 4 weeks of sunitinib in metastatic RCC patients.

OUTLINE:

Patients receive sunitinib malate orally (PO) daily for 4 weeks. Patients undergo neuromuscular testing at baseline and on day 28 and complete fatigue assessment at baseline and on days 14 and 28. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01740154
Study type	Interventional
Source	Case Comprehensive Cancer Center
Contact
Status	Terminated
Phase	N/A
Start date	September 2012
Completion date	March 2014

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