Stage IV Non-small Cell Lung Cancer Clinical Trial
Official title:
Phase II Study of Antineoplastons A10 and AS2-1 Capsules In Patients With Non Small Cell Lung Cancer
Current therapies for Stage IV non-small cell lung cancer provide very limited benefit to the
patient. The anti-cancer properties of Antineoplaston therapy suggest that it may prove
beneficial in the treatment of Stage IV lung cancer
PURPOSE: This study is being performed to determine the effects (good and bad) that
Antineoplaston therapy has on patients with Stage IV lung cancer.
Stage IV non-small cell lung cancers receive Antineoplaston A10 and AS2-1 capsules orally six
to seven times a day. Treatment continues in the absence of disease progression or
unacceptable toxicity.
OBJECTIVES:
- To determine the efficacy of Antineoplaston therapy in patients with Stage IV non-small
cell lung cancer, as measured by an objective response to therapy (complete response,
partial response or stable disease).
- To determine the safety and tolerance of Antineoplaston therapy in patients with Stage
IV non-small cell lung cancer.
- To determine objective response, tumor size is measured utilizing MRI scans, which are
performed every 4 months for 2 years, every 6 months for 2 years, and then annually for
2 years thereafter.
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