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Stage IV Cutaneous Melanoma clinical trials

View clinical trials related to Stage IV Cutaneous Melanoma.

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NCT ID: NCT05079113 Active, not recruiting - Stage III Melanoma Clinical Trials

Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting

Start date: October 1, 2019
Phase:
Study type: Observational

To generate meaningful data regarding ctDNA that would infer risk of recurrence in stage III melanoma patients.

NCT ID: NCT03590054 Completed - Metastatic Melanoma Clinical Trials

Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies

Start date: August 20, 2018
Phase: Phase 1
Study type: Interventional

This phase I trial studies the best dose and side effects of abexinostat and how well it works with given together with pembrolizumab in treating participants with microsatellite instability (MSI) solid tumors that have spread to other places in the body. Abexinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as pembrolizumab, may interfere with the ability of tumor cells to grow and spread. Giving abexinostat and pembrolizumab may work better in treating participants with solid tumors.

NCT ID: NCT03396952 Completed - Clinical trials for Stage IV Cutaneous Melanoma

Prostaglandin Inhibition and Immune Checkpoint Blockade in Melanoma

Start date: April 19, 2018
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well pembrolizumab, ipilimumab, and aspirin work in treating patients with melanoma that has spread to other places in the body or cannot be removed by surgery. Monoclonal antibodies, such as pembrolizumab and ipilimumab, may interfere with the ability of tumor cells to grow and spread. Aspirin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving pembrolizumab, ipilimumab, and aspirin may work better in treating patients with melanoma.

NCT ID: NCT02587650 Terminated - Clinical trials for ALK Fusion Protein Expression

Capmatinib, Ceritinib, Regorafenib, or Entrectinib in Treating Patients With BRAF/NRAS Wild-Type Stage III-IV Melanoma

Start date: March 26, 2015
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well capmatinib, ceritinib, regorafenib, or entrectinib work in treating patients with BRAF/NRAS wild-type stage III-IV melanoma. Capmatinib, ceritinib, regorafenib, or entrectinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.