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Stage 4S Neuroblastoma clinical trials

View clinical trials related to Stage 4S Neuroblastoma.

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NCT ID: NCT01418495 Completed - Pain Clinical Trials

Pharmacokinetics of Ch14.18 in Younger Patients With High-Risk Neuroblastoma

Start date: May 26, 2011
Phase:
Study type: Observational

This research trial is studying how Ch14.18 acts in the body of younger patients with high-risk neuroblastoma. Studying samples of blood from patients with cancer receiving Ch14.18 may help doctors learn more about how this drug is used by the body to develop better ways to give the drug to potentially improve its effectiveness and lessen its side effects.

NCT ID: NCT01358617 Completed - Clinical trials for Recurrent Neuroblastoma

Prognostic Biomarkers in Tumor Tissue Samples From Young Patients With Neuroblastoma

Start date: May 2011
Phase: N/A
Study type: Observational

This research study is studying biomarkers in tumor tissue samples from young patients with neuroblastoma. Studying samples of tissue from patients with cancer in the laboratory may help doctors identify biomarkers and learn more about biomarkers related to cancer

NCT ID: NCT01208454 Completed - Clinical trials for Recurrent Neuroblastoma

Vorinostat and Isotretinoin in Treating Patients With High-Risk Refractory or Recurrent Neuroblastoma

Start date: December 2010
Phase: Phase 1
Study type: Interventional

This phase I trial is studying the side effects and the best dose of vorinostat when given together with isotretinoin to see how well it works in treating patients with high-risk refractory or recurrent neuroblastoma. Vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Isotretinoin may help vorinostat work better by making tumor cells more sensitive to the drug. Giving vorinostat together with isotretinoin may be an effective treatment for neuroblastoma.

NCT ID: NCT00958659 Completed - Clinical trials for Localized Unresectable Neuroblastoma

Study of Specimens From Young Patients With Neuroblastoma

Start date: December 2008
Phase: N/A
Study type: Observational

This research trial studies specimens from young patients with neuroblastoma. Studying the genes expressed in specimens from patients with cancer may help doctors identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment.

NCT ID: NCT00898391 Completed - Clinical trials for Recurrent Neuroblastoma

Study of DNA in Blood Samples From Patients With Neuroblastoma

Start date: June 2007
Phase: N/A
Study type: Observational

This research trial studies is deoxyribonucleic acid (DNA) in blood samples from patients with neuroblastoma. Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment.

NCT ID: NCT00567567 Completed - Clinical trials for Recurrent Neuroblastoma

Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma

Start date: November 5, 2007
Phase: Phase 3
Study type: Interventional

This randomized phase III trial compares two different high-dose chemotherapy regimens followed by a stem cell transplant in treating younger patients with high-risk neuroblastoma. Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving combination chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving these treatments before a peripheral blood stem cell transplant helps kill any tumor cells that are in the body and helps make room in the patient?s bone marrow for new blood-forming cells (stem cells) to grow. After treatment, stem cells are collected from the patient's blood and stored. High-dose chemotherapy and radiation therapy is then given to prepare the bone marrow for the stem cell transplant. The stem cells are then returned to the patient to replace the blood-forming cells that were destroyed by the high- chemotherapy. It is not yet known which regimen of high-dose chemotherapy is more effective for patients with high-risk neuroblastoma undergoing a peripheral blood stem cell transplant.

NCT ID: NCT00033293 Completed - Clinical trials for Localized Unresectable Neuroblastoma

Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma

Start date: March 15, 2004
Phase: Phase 3
Study type: Interventional

This randomized phase III trial is studying cyclophosphamide, prednisone, and immunoglobulin to see how well they work compared to cyclophosphamide and prednisone alone in treating patients with abnormal trunk muscle movements associated with neuroblastoma. Drugs used in chemotherapy, work in different ways to stop tumor cells from dividing so they stop growing or die. Steroid therapy decreases inflammation. Combining chemotherapy and steroid therapy with immunoglobulin may be effective in treating abnormal muscle movement associated with neuroblastoma.