ST-segment Myocardial Infarction Clinical Trial
Official title:
Postconditioning Used to Limit Final Infarct Size in Patients With Acute ST-segment Elevation Myocardial Infarction
Standard treatment of patients with acute ST-segment elevation myocardial infarction consist
of acute re-opening of the occluded coronary artery (primary PCI). Despite successful
treatment of the epicardial vessel reperfusion is sometimes inadequate leading to large
final infarct sizes. This phenomenon is known as the reperfusion injury. Several animal
studies have indicated that graded re-opening of the artery may limit tissue damage.
Generally this is referred to as mechanical postconditioning.
The study investigates the effect on final infarct size evaluated by magnetic resonance scan
of postconditioning of ST-segment elevation myocardial infarctions. Mechanical
postconditioning is performed by means of several balloon inflations in the injured vessel
following its acute re-opening.
Please see above ;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment