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Patient-derived Xenograft Models of Tumor From Patients With Head and Neck Cancer — UCL-Xenog  

Squamous Cell Carcinoma of the Head and Neck Clinical Trial

Official title:
Establishment of Primary Patient-derived Xenograft Models of Tumor From Patients With Head and Neck Cancer for Preclinical Evaluation of Targeted Therapies.

Clinical Trial Summary

The investigators want to have a collection of fresh primary or recurrent tumor tissue for establishment of patients-derived xenografts in order to: generate a biobank of in vivo patient xenografts representing the different subgroups of tumors for head and neck cancer - perform genetic and transcriptional profiling of the primary, metastatic tumors and xenograft tumors - evaluate the efficacy of new targeted agents, whether or not in combination with standard treatment options - evaluate biomarkers of drug sensitivity - study primary and secondary (acquired) resistance in these models

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02572778
Study type Observational
Source Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Contact Aline Gillain, MedSciences
Phone 00322764
Email aline.gillain@uclouvain.be
Status Recruiting
Phase
Start date September 2015
Completion date December 2025
View Details
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