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Sprains and Strains clinical trials

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NCT ID: NCT01518335 Completed - Sprain of Ankle Clinical Trials

Use of Platelet Rich Plasma Therapy for Acute Ankle Sprains in the Emergency Department

PRP
Start date: June 2009
Phase: N/A
Study type: Interventional

This research study hopes to determine whether or not platelet rich plasma therapy improves healing time of moderate to severe ankle sprain in comparison to standard of care therapy.

NCT ID: NCT01509456 Completed - Body Weight Changes Clinical Trials

The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation

NUC
Start date: February 2010
Phase: N/A
Study type: Interventional

Mainly due to the absence of gravitational forces in weightlessness, astronauts suffer from an increased bone loss- negatively affecting health and vitality during a mission. The development of effective countermeasures to this loss includes many different aspects like sports but also nutrition. Alkaline salts, abundant in fruits and vegetables, have shown to have positive effects on markers of bone turnover of postmenopausal women but also men and younger adults. With the current study the effects of a potassium bicarbonate supplementation added to a standardised, strictly controlled, definite diet of healthy, young men, should be verified within 21 days of 6°- HDT- Bedrest- the gold standard of simulating weightlessness within earthbound conditions.

NCT ID: NCT01449760 Completed - Ankle Sprain Clinical Trials

Ankle Sprain Rehabilitation With the Wii Balance Board

Start date: March 2010
Phase: N/A
Study type: Interventional

Physical activity and in particular sport is beneficial to health. Nevertheless, some of these activities may create a risk of injury. Ankle sprain is the most common sport related injury. Sports that are causing the highest number of ankle sprains are: football (30%), handball-basketball-volleyball-rugby (24%), gymnastics sports (6%), skiing (6%), cycling (6%), athletics (4%) and contact sports (4%). A recent study in the Netherlands identified a total of 1.3 million sports injuries. 47% of these patients required medical care. The total costs (direct and indirect) were assessed 84.240.000 EUR per year. Prospective studies demonstrated that athletes with a ankle sprain have a twofold risk of re-injury during the first year after the trauma, and in half of patients with an ankle sprain recurrence this could lead to instability or chronic pain of the ankle. The Wii Balance Board ® is a tool that is increasingly used in the field of health. In some hospitals, therapists are beginning to use it for the rehabilitation of patients after surgery, fractures or strokes. Patients are asked to complete their physical therapy session by practicing "sports" via video games such as skiing, bowling or hula hoop. Currently, there are no randomized controlled studies that publish on the effectiveness of this tool. Recently, a study investigated the efficacy of the Wii Balance Board ® to improve balance, strength, joint mobility and level of physical activity. After 10 weeks of training, people an increased strength and balance was found. However, these results still require statistical confirmation. Thus this objectives of this study are - To assess the efficacy of exercise training with the Wii Balance Board ® Platform - To evaluate the effectiveness of physical therapy (based on current guidelines) - To compare these two types of care (conventional physiotherapy versus Wii) to a control group (non-treatment).

NCT ID: NCT01430858 Completed - Osteoporosis Clinical Trials

Does Vibration Therapy Induce Higher Than Normal Bone Strains and Strain Rates Than Those Experienced During Habitual Daily Activities

Start date: March 2011
Phase: N/A
Study type: Interventional

The overall aim of this study is to test the hypothesis that vibration exercise can induce higher than normal bone strains and strain rates than are experienced during habitual locomotor activities. The investigators plan to study healthy young volunteers to: 1. Determine the relationship between tibial bone strain and - the frequency and amplitude of vibration therapy - a range of habitual locomotor activities; 2. Determine the transmission of vibrations during vibration therapy, in terms of - amplitude attenuation and phase shift of positional coordinates and accelerations at anatomic landmarks along the lower leg and other skeletal sites - the relationship between these and different frequencies and amplitudes of vibration therapy; 3. Determine the muscle power in the lower limb associated with various habitual locomotor activities and its relationship to the measured tibial bone strain. The investigators subsequently hope to use the data captured in this experiment to develop a QCT-based finite element (FE) model of the human lower limb (tibia, fibula and foot). The investigators will then validate this model in relation to the characteristics (amplitude and phase shift) of the measured tibial bone strain and transmission of vibrations to the different anatomical landmarks during vibration therapy.

NCT ID: NCT01198834 Completed - Ankle Sprains Clinical Trials

MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle Sprains

Start date: September 2010
Phase: Phase 3
Study type: Interventional

A Randomized, Multi-Center, Double-Blind, Factorial, Comparator and Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle Sprains

NCT ID: NCT01134653 Completed - Ankle Sprain Clinical Trials

A Comparison of Early Mobilization Versus Traditional Treatment for Acute Ankle Sprains.

Start date: January 2010
Phase: N/A
Study type: Interventional

Acute ankle sprain is one of the most common musculoskeletal injuries, accounting for an estimated 2 million injuries per year and 20% of all sports injuries in the United States. Ankle sprains can lead to prolonged periods of pain, difficulty with mobility, and lost work or play time. Current best practice guidelines for treatment of an acute ankle sprain are protection, rest, ice, compression and elevation (PRICE). However recent systematic reviews for ankle sprains call into question this treatment. Two critical components; immobilization and ice, have little or no evidence of efficacy for ankle sprain. Interestingly, mobilization appears to be more effective at reducing the pain, swelling and stiffness of musculoskeletal injuries including ankle sprains. Historically the limitation to early mobilization has been pain. Recently developed stretch bands have been introduced to the therapy market as a tool that allows pain-free active and resisted ankle movement after acute ankle sprain. The investigators propose a double blind randomized controlled study to compare 2 ankle sprain treatments on their ability to speed recovery and reduce morbidities such as pain, swelling and weakness.

NCT ID: NCT01054820 Completed - Acute Back Strain Clinical Trials

Study to Assess the Effectiveness and Safety of FLECTOR Patch for Treatment of Acute Back Strain

Start date: January 2010
Phase: Phase 4
Study type: Interventional

Although approved for minor strains, sprains and contusions, FLECTOR Patch has not been studied extensively in the setting of acute back strain. This study is being conducted as an initial step in demonstrating the benefit of FLECTOR Patch specifically for back strain. In particular, this study is expected to provide information about the amount of improvement in back strain among subjects using the FLECTOR Patch, which may then be used to inform subsequent studies.

NCT ID: NCT01037816 Completed - Ankle Sprain Clinical Trials

FS-67 in the Treatment of Pediatric Patients With Ankle Sprain

Start date: December 2009
Phase: Phase 4
Study type: Interventional

The objective of this study is assess the efficacy and safety of single and multiple applications of the FS-67 patch in the treatment of ankle sprain in pediatric population (ages 13-17).

NCT ID: NCT01021111 Active, not recruiting - Wounds and Injuries Clinical Trials

The Design and Evaluation of an Active Intervention for the Prevention of Non-contact ACL Injury

Start date: November 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The overall goal of this project is to reduce the risk for anterior cruciate ligament injuries by designing a targeted intervention that will alter the known kinematic and kinetic risk factors associated with ACL injuries. This study will address the following specific aims: 1) To optimize a wearable, targeted, active training feedback device to reduce the risk of ACL injury among healthy subjects by inducing patterns of movement that alter the known kinematic and kinetic risk factors associated with ACL injuries. 2) To evaluate the efficacy of the active device and determine if the device reduces the risk of ACL injury among healthy subjects by effectively inducing patterns of movement that alter the known kinematic and kinetic risk factors associated with ACL injuries.

NCT ID: NCT00981331 Terminated - Clinical trials for Ankle Inversion Sprain

Changes in the Ankle Range of Motion Following Subtalar Joint Manipulation

Start date: May 2010
Phase: N/A
Study type: Interventional

The purpose of the study is to determine whether manipulation of the subtalar joint (one of the two joints of the ankle) has an effect on ankle range of motion in a group of ankles that have sustained a subacute inversion ankle sprain. The investigators expect subtalar joint manipulation will increase ankle range of motion about the subtalar joint, but not at the talocrural joint (the other joint of the ankle).