Clinical Trials Logo

Spondylolisthesis clinical trials

View clinical trials related to Spondylolisthesis.

Filter by:
  • Not yet recruiting  
  • Page 1 ·  Next »

NCT ID: NCT06447194 Not yet recruiting - Clinical trials for Degenerative Disc Disease

Effect of RECK in Posterior Spinal Fusion

Start date: April 1, 2025
Phase: Phase 1/Phase 2
Study type: Interventional

"RECK" is a combination of local anesthesia medications, used for the purpose of pain control. RECK is an acronym which stands for Ropivacaine, Epinephrine, Clonidine, and Ketorolac. The purpose of this study is to investigate the effect of RECK local injectable anesthetic in the setting of posterior spinal fusion. Our specific aims are the following. Primary aim: to investigate the effect of RECK local injectable anesthetic on postoperative VAS pain scores. Secondary aims: to investigate of effect of RECK injection on postoperative opioid consumption and hospital length of stay. Hypothesis: RECK injection will significantly decrease postoperative VAS pain score, opioid consumption, and hospital length of stay compared to placebo controls.

NCT ID: NCT06320899 Not yet recruiting - Clinical trials for Degenerative Spondylolisthesis

Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine Diseases

Start date: April 2, 2024
Phase: N/A
Study type: Interventional

The purpose of this multi-center, randomized, clinical study is to show that the treatment of degenerative lumbar spine with high- or mid-flex rods is not inferior to the treatment with low-flex rods in terms of clinical and safety-related results. The primary aim is to compare the reduction in back pain after the treatment with high- or mid-flex rods with that after treatment with low-flex rods. Secondary, the functionality after treatment with high- or mid-flex rods will be compared to that after treatment with low-flex rods.

NCT ID: NCT06255366 Not yet recruiting - Clinical trials for Lumbar Spondylolisthesis

Analysis of the Clinical Efficacy of Intravenous Application of Hemostatic Drugs in Improving the Clarity of Vision Under Endoscope, Perioperative Bleeding Volume and Anti-inflammatory Effect of Spinal Endoscopic Lumbar Fusion

Start date: March 28, 2024
Phase: Phase 4
Study type: Interventional

To study the clinical efficacy of carosodiumsulfonate and desmopressin in improving the clarity of vision under endoscope, perioperative bleeding volume and anti-inflammatory effect in endoscopic lumbar fusion

NCT ID: NCT06000319 Not yet recruiting - Clinical trials for Degenerative Disc Disease

Natural Matrix Protein™ (NMP™) Fibers in Cervical and Lumbar Interbody Fusion

Start date: September 2023
Phase:
Study type: Observational

The aim of this study is to evaluate the effectiveness and safety of Natural Matrix Protein™ (NMP™) fibers when used in cervical or lumbar interbody fusion in patients with degenerative disc disease (DDD), spinal stenosis, spondylolisthesis undergoing cervical or lumbar interbody spine fusion at no more than 3 adjacent levels.

NCT ID: NCT05691062 Not yet recruiting - Spine Fusion Clinical Trials

Titanium vs. PEEK Fusion Devices in 1 Level TLIF

TLIF
Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

The objective of this study is to evaluate and follow the clinical and radiographic outcomes of patients undergoing 1 level TLIF randomized to either a titanium or a PEEK spacer to 24 months after surgery.

NCT ID: NCT05610397 Not yet recruiting - Clinical trials for Degenerative Disc Disease

Retrospective Study With Patients Treated With STALIF® C or M and Ti or FLX Implants for 1 and 2 Levels

Stalif
Start date: April 24, 2023
Phase:
Study type: Observational

This is a Retrospective, Observational Multi-Center study, utilizing patients diagnosed with up to a Grade1 spondylolisthesis or retrolisthesis or symptomatic degenerative disc disease and treated with STALIF® C, or M, Ti and/or FLX implants at one or two levels.

NCT ID: NCT05480267 Not yet recruiting - Clinical trials for Lumbar Spondylolisthesis

A RCT of UBE vs. MIS-TLIF in Lumbar Spondylolisthesis

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

Unilateral biportal endoscopy (UBE) is a new spinal minimally invasive technique improved for the treatment of lumbar spondylolisthesis (LSP). The present study aims to establish a multicenter, large sample, randomized controlled study to explore the technical advantages and surgical indications of this new technique in the treatment of LSP by comparing with the classical minimally invasive posterior spinal interbody fusion; to compare the postoperative clinical and imaging results and analyze the surgical complications and preventive measures.

NCT ID: NCT05464134 Not yet recruiting - Clinical trials for Lumbar Spondylolisthesis

Incidence of Lumbar Spondylolisthesis in Patients Candidate for TKR

Start date: May 2023
Phase:
Study type: Observational

This study aims to detect the incidence of spondylolisthesis in patients candidate for Total knee replacement (TKR) and to investigate the effect of TKR on the course of low back pain.

NCT ID: NCT04559399 Not yet recruiting - Clinical trials for Isthmic Spondylolisthesis

Smiley Face Shaped Rod Technique Versus Instrumented Posteriolateral Fusion in Treatment of Isthmic Lumbar Spondylolisthesis

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Aim of research is to investigates clinical, surgical and radiological outcome of vertebral pars intetarticularis repair by used smile face shape rod technique and bone grafting and comparing that with posteriolateral fusion with used traditional transpedical screw and rod fixation in management of isthmic spondylistheisis

NCT ID: NCT04447950 Not yet recruiting - Spondylolisthesis Clinical Trials

Randomized Control Trial of Quadratus Lumborum Block for Lumbar Spine Decompression and Fusion Surgery

Start date: June 2020
Phase: N/A
Study type: Interventional

Lumbar spinal decompression and fusion is a commonly performed procedure fro neural impingement and back pain from a variety of pathologies. The importance of pain control in the postoperative period for spinal surgery has been discussed and proven extensively, with both immediate and delayed reduction in complications and improved clinical results. Quadratus lumborum (QL) block was introduced in 2007 and is performed under ultrasound guidance for perioperative pain management in various surgeries.However, the plane for a posterior QL block can be easily reached during open midline spinal surgery. The investigators hypothesize that the posterior QL block is an effective analgesic tool for lumbar laminectomy surgery, because in lumbar laminectomy the quadratus lumborum is already exposed and is in direct visual contact. For that reason it is imperative to test the benefits of this procedure. This is a double blinded randomized control study to assess the results of intra-operative QL block performed for lumbar decompression and fusion.