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Spondylolisthesis clinical trials

View clinical trials related to Spondylolisthesis.

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NCT ID: NCT06320899 Not yet recruiting - Clinical trials for Degenerative Spondylolisthesis

Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine Diseases

Start date: April 2, 2024
Phase: N/A
Study type: Interventional

The purpose of this multi-center, randomized, clinical study is to show that the treatment of degenerative lumbar spine with high- or mid-flex rods is not inferior to the treatment with low-flex rods in terms of clinical and safety-related results. The primary aim is to compare the reduction in back pain after the treatment with high- or mid-flex rods with that after treatment with low-flex rods. Secondary, the functionality after treatment with high- or mid-flex rods will be compared to that after treatment with low-flex rods.

NCT ID: NCT06255366 Not yet recruiting - Clinical trials for Lumbar Spondylolisthesis

Analysis of the Clinical Efficacy of Intravenous Application of Hemostatic Drugs in Improving the Clarity of Vision Under Endoscope, Perioperative Bleeding Volume and Anti-inflammatory Effect of Spinal Endoscopic Lumbar Fusion

Start date: March 28, 2024
Phase: Phase 4
Study type: Interventional

To study the clinical efficacy of carosodiumsulfonate and desmopressin in improving the clarity of vision under endoscope, perioperative bleeding volume and anti-inflammatory effect in endoscopic lumbar fusion

NCT ID: NCT06154005 Not yet recruiting - Clinical trials for Degenerative Disc Disease

OsteoAdapt SP Advanced Bone Graft Feasibility Study - Transforaminal Interbody Lumbar Fusion

OASIS
Start date: March 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this clinical study is to assess the safety and effectiveness of the OsteoAdapt SP as a replacement for the autograft standard of care bone graft within the interbody cage, as well as identify the OsteoAdapt SP dose to be investigated in a future pivotal study.

NCT ID: NCT06093477 Not yet recruiting - Spondylolisthesis Clinical Trials

Studying Melatonin and Recovery in Teens

SurgerySMART
Start date: July 2024
Phase: N/A
Study type: Interventional

The goal of this feasibility clinical trial is to learn if melatonin can help teens having spinal fusion surgery by promoting healthy sleep. Melatonin is available as a dietary supplement that may be effective in promoting longer, higher quality sleep. This study will assess the feasibility and acceptability of melatonin for teens undergoing spinal fusion surgery, as well as determine optimal measured outcomes (sleep, pain, health-related quality of life) at short- and long-term follow-up.

NCT ID: NCT06000319 Not yet recruiting - Clinical trials for Degenerative Disc Disease

Natural Matrix Protein™ (NMP™) Fibers in Cervical and Lumbar Interbody Fusion

Start date: September 2023
Phase:
Study type: Observational

The aim of this study is to evaluate the effectiveness and safety of Natural Matrix Protein™ (NMP™) fibers when used in cervical or lumbar interbody fusion in patients with degenerative disc disease (DDD), spinal stenosis, spondylolisthesis undergoing cervical or lumbar interbody spine fusion at no more than 3 adjacent levels.

NCT ID: NCT05691062 Not yet recruiting - Spine Fusion Clinical Trials

Titanium vs. PEEK Fusion Devices in 1 Level TLIF

TLIF
Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

The objective of this study is to evaluate and follow the clinical and radiographic outcomes of patients undergoing 1 level TLIF randomized to either a titanium or a PEEK spacer to 24 months after surgery.

NCT ID: NCT05610397 Not yet recruiting - Clinical trials for Degenerative Disc Disease

Retrospective Study With Patients Treated With STALIF® C or M and Ti or FLX Implants for 1 and 2 Levels

Stalif
Start date: April 24, 2023
Phase:
Study type: Observational

This is a Retrospective, Observational Multi-Center study, utilizing patients diagnosed with up to a Grade1 spondylolisthesis or retrolisthesis or symptomatic degenerative disc disease and treated with STALIF® C, or M, Ti and/or FLX implants at one or two levels.

NCT ID: NCT05538416 Not yet recruiting - Clinical trials for Degenerative Spondylolisthesis

Short-term Clinical Outcome of Cortical Bone Trajectory Compared With the Traditional "Open" and Minimal Invasive Posterior Lumbar Interbody Fusion

Start date: September 2022
Phase:
Study type: Observational

A combined prospective cohort study and retrospective analysis of previously collected data. Three different techniques for posterior lumbar interbody fusion (PLIF) are compared: CBT-PLIF, MI-PLIF and open PLIF. A total of 180 patients are included, who will be followed up to 6 weeks postoperatively.

NCT ID: NCT05480267 Not yet recruiting - Clinical trials for Lumbar Spondylolisthesis

A RCT of UBE vs. MIS-TLIF in Lumbar Spondylolisthesis

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

Unilateral biportal endoscopy (UBE) is a new spinal minimally invasive technique improved for the treatment of lumbar spondylolisthesis (LSP). The present study aims to establish a multicenter, large sample, randomized controlled study to explore the technical advantages and surgical indications of this new technique in the treatment of LSP by comparing with the classical minimally invasive posterior spinal interbody fusion; to compare the postoperative clinical and imaging results and analyze the surgical complications and preventive measures.

NCT ID: NCT05464134 Not yet recruiting - Clinical trials for Lumbar Spondylolisthesis

Incidence of Lumbar Spondylolisthesis in Patients Candidate for TKR

Start date: May 2023
Phase:
Study type: Observational

This study aims to detect the incidence of spondylolisthesis in patients candidate for Total knee replacement (TKR) and to investigate the effect of TKR on the course of low back pain.