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Spondylitis clinical trials

View clinical trials related to Spondylitis.

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NCT ID: NCT01586650 Completed - Clinical trials for Ankylosing Spondylitis

Effects of Aerobic Training in Patients With Ankylosing Spondylitis

Start date: July 2011
Phase: Phase 3
Study type: Interventional

This is a randomized controlled trial with blinded assessor on the effects of aerobic exercise (walking)in patients with Ankylosing Spondylitis.

NCT ID: NCT01583374 Completed - Clinical trials for Ankylosing Spondyloarthritis

Study of Apremilast to Treat Subjects With Active Ankylosing Spondylitis

POSTURE
Start date: May 2, 2012
Phase: Phase 3
Study type: Interventional

Apremilast is a new, orally available, small molecule drug that specifically inhibits phosphodiesterase 4 (PDE4), an enzyme that modulates inflammatory cytokines. This clinical study tests whether apremilast can improve the signs and symptoms of ankylosing spondylitis.

NCT ID: NCT01577563 Completed - Clinical trials for Rheumatoid Arthritis (RA)

Prevalence Study of Gastrointestinal Risk Factors in Patients With Osteoarthritis (OA), Rheumatoid Arthritis (RA) and Ankylosing Spondylitis (AS).

RATIONAL
Start date: May 2012
Phase: N/A
Study type: Observational

RATIONAL is a multinational, multicentre, observational, cross sectional study of adult patients in treatment with NSAID therapy for OA, RA or AS during for at least 2 weeks before study visit (at least one dose).

NCT ID: NCT01571206 Completed - Clinical trials for Ankylosing Spondylitis

An Extension Study to Demonstrate the Equivalence of Long-Term Efficacy and Safety of CT-P13 in Patients With Ankylosing Spondylitis Who Were Treated With Infliximab (Remicade or CT-P13) in Study CT-P13 1.1

Start date: March 2012
Phase: Phase 1
Study type: Interventional

This open-label, single-arm, multicenter, multiple single-dose intravenous (IV) infusion, efficacy, and safety extension study of the Phase 1 Study CT-P13 1.1 is designed to assess the long-term efficacy and safety of multiple doses of CT-P13.

NCT ID: NCT01567878 Completed - Clinical trials for Spondylitis, Ankylosing

Ultrasound of Enthesis in Patients With Ankylosing Spondylitis: a Comparative Study With Health Subjects

Start date: May 2009
Phase: N/A
Study type: Observational

- Evaluate the correlation of ultrasound MASEI index with clinical, functional, radiographic and laboratorial variables in patients with ankylosing spondylitis. - Evaluate correlation between articular (shoulders, hips, knees and ankles) ultrasound (synovitis, erosions, power doppler) with same variables. - Evaluate correlation between articular and enthesis ultrasound exam in this study. - Compare patients and healthy individuals data, to calculate the ROC curve to estimate predictor value of disease.

NCT ID: NCT01519375 Completed - Clinical trials for Rheumatoid Arthritis

Assessment of NSAID-treated Patients Adherence to Co-prescribed Proton Pump Inhibitor (PPI)

CONVOY
Start date: March 2012
Phase: N/A
Study type: Observational

The primary objective of this cross-sectional observational real life study is to investigate the patient reported adherence to PPI, when prescribed as prevention of NSAID associated GI Ulcers to patients prescribed a NSAID. Patients included have Osteoarthritis, Rheumatoid Arthritis or Ankylosing Spondylitis. Adherence will be assessed by patient questionnaires.

NCT ID: NCT01517620 Completed - Clinical trials for Ankylosing Spondylitis

Total Glucosides Paeony Capsules in Maintaining Clinical Remission in Patients With Ankylosing Spondylitis Which Achieve Clinical Remission After Anti-TNF Therapy

Start date: November 2011
Phase: Phase 4
Study type: Interventional

This is a prospective, randomized, open-label clinical trial to evaluate the efficacy and safety of total glucosides paeony capsules in maintaining clinical remission in patients with ankylosing spondylitis which achieved clinical remission after anti-TNF therapy. Patients will be divided into two groups randomly, one group receive non-steroid anti-inflammatory drugs(NSAID) mono-therapy and the other group receive total glucosides paeony capsules plus NSAID therapy for 24 weeks. The primary clinical endpoint is the proportion of patients which disease activity reaches relapse criteria. The investigator's hypothesis the proportion of relapse in total glucosides paeony capsules plus NSAID group would be lower than the NSAID mono-therapy group.

NCT ID: NCT01511926 Completed - Clinical trials for Rheumatoid Arthritis

Descriptive Study in Patients Treated With Vimovo™, Including Registration of the Physicians' Prescribing Patterns

CHARACTERIZE
Start date: January 2012
Phase: N/A
Study type: Observational

The most common pain-relievers used by patients with rheumatic disorders are called non-steroidal anti-inflammatory drugs (NSAIDs). These drugs are effective and well documented, but they can cause ulcers and gastrointestinal side effects. Vimovo™ is a tablet containing naproxen (NSAID) and a gastroprotective agent called esomeprazole. Patients with rheumatic disorders, who are at risk for developing gastrointestinal side effects, and where lower doses of naproxen or other NSAID treatment is not considered sufficient, could use this tablet. The regulatory authorities in many European countries have approved the use of Vimovo™, but they would like to understand how various factors influence the doctors' decision to prescribe the tablet and what is characterizing the patients receiving it. The aim of the study is to answer these questions.

NCT ID: NCT01474876 Completed - Psoriatic Arthritis Clinical Trials

Multi-country Post-Marketing Observational Study on Maintenance of Effectiveness of Adalimumab (Humira®) in Patients With Ankylosing Spondylitis and Psoriatic Arthritis

Start date: November 2011
Phase: N/A
Study type: Observational

This 12-month postmarketing observational study (PMOS) was a prospective, single-arm, multicenter, multi-country study, with follow-up visits at 3, 6, 9, and 12 months after the initial baseline visit. The study was conducted to determine the long-term effectiveness of treatment with adalimumab in routine clinical use in participants with Ankylosing Spondylitis (AS) and Psoriatic Arthritis (PsA) in Central and Eastern European Countries.

NCT ID: NCT01463189 Completed - Clinical trials for Rheumatoid Arthritis

Web-based Support to Manage Arthritis Pain

Start date: September 2011
Phase: Phase 2
Study type: Interventional

Development of an interactive, online pain self-management program for adults who suffer from pain associated with osteoarthritis, rheumatoid arthritis, Ankylosing spondylitis, and other arthritic conditions (e.g., psoriatic arthritis) using principles from Social Cognitive Theory (Bandura, 1977). This online health intervention, painACTION: Arthritis, will provide clinically reliable information about diagnosis, treatment, and management of arthritis, written for health consumers in a clear and engaging manner to help increase their skills and confidence to use self-management strategies.