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Spondylitis, Ankylosing clinical trials

View clinical trials related to Spondylitis, Ankylosing.

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NCT ID: NCT05119712 Withdrawn - Clinical trials for Ankylosing Spondylitis

Terbinafine Treatment of Axial Spondyloarthropathy

FUN
Start date: March 9, 2021
Phase: Early Phase 1
Study type: Interventional

This is a pilot study to determine if further research is warranted to assess if anti-fungal therapy is an effective adjunctive treatment for axial spondyloarthropathy

NCT ID: NCT04483700 Withdrawn - Clinical trials for Ankylosing Spondylitis

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Are Naive to Biologic Disease-Modifying Antirheumatic Drug Therapy

SEALION2-NAÏVE
Start date: December 2020
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the effect of filgotinib versus placebo on signs and symptoms of active ankylosing spondylitis (AS), evaluated by Assessment of SpondyloArthritis international Society 40% improvement (ASAS40) response at Week 16 in participants with active AS who are naive to biologic disease-modifying antirheumatic drug therapy.

NCT ID: NCT04483687 Withdrawn - Clinical trials for Ankylosing Spondylitis

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Have an Inadequate Response to Biologic Disease-Modifying Antirheumatic Drug Therapy

SEALION1-IR
Start date: December 2020
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the effect of filgotinib versus placebo on signs and symptoms of active ankylosing spondylitis (AS), evaluated by Assessment of SpondyloArthritis international Society 40% improvement (ASAS40) response at Week 16 in participants with active AS who have an inadequate response to biologic disease-modifying antirheumatic drug therapy.

NCT ID: NCT03937271 Withdrawn - Clinical trials for Rheumatoid Arthritis

Objective Measurement Methods for Autoimmune Disease and Dry Eye Syndrome

Start date: April 1, 2019
Phase:
Study type: Observational

To explore the association among TCM pattern, TCM tongue diagnosis and TCM pulse diagnosis for Autoimmune disease and Dry eye syndrome

NCT ID: NCT01870284 Withdrawn - Clinical trials for Spondylitis, Ankylosing

Study of Ixekizumab in Participants With Active Ankylosing Spondylitis (AS)

SPIRIT A1
Start date: July 2014
Phase: Phase 3
Study type: Interventional

This study will assess the safety and efficacy of ixekizumab (LY2439821) compared to placebo in participants with active AS.

NCT ID: NCT01692457 Withdrawn - Clinical trials for Rheumatoid Arthritis

A Study to Assess the Safety and Effectiveness of Golimumab in Filipino Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

Start date: July 2013
Phase: Phase 4
Study type: Observational

The purpose of this study is to assess the safety and effectiveness of golimumab for the treatment of rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis among Filipino patients.

NCT ID: NCT01148901 Withdrawn - Clinical trials for Ankylosing Spondylitis

Effectiveness and Safety of Early Treatment With Infliximab for Hip Arthritis Associated With Ankylosing Spondylitis (AS) (P06451)

HACER
Start date: June 2010
Phase: Phase 4
Study type: Interventional

This trial is designed to measure improvement of hip involvement in patients with ankylosing spondylitis (AS) after receiving 4 doses of infliximab. Participants will receive infliximab 5 mg/kg (as an intravenous perfusion over a period of 2 hours) at Weeks 0, 2, 6, and 14, consistent with the approved dosing regimen described in the label. Participants will be evaluated for hip pain, functional capacity and stiffness before and after 14 weeks (4 doses) of treatment. Further treatment after 4 doses is based on standard clinical practice as determined by the trial site.

NCT ID: NCT00298012 Withdrawn - Clinical trials for Spondylitis, Ankylosing

Methotrexate in the Treatment of Axial Spondyloarthritis

Start date: March 2006
Phase: Phase 4
Study type: Interventional

The goal of this study is to evaluate the efficacy of oral methotrexate for the treatment of active axial spondyloarthritis (early ankylosing spondylitis or spondyloarthritis with sacroiliitis). Efficacy will be measured by reduction in the signs and symptoms of active spondyloarthritis including effects on back pain and stiffness, range of motion in the spine, physical function, quality of life and incidence of arthritis, enthesitis and anterior uveitis.