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Spondylitis, Ankylosing clinical trials

View clinical trials related to Spondylitis, Ankylosing.

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NCT ID: NCT05792358 Enrolling by invitation - Clinical trials for Ankylosing Spondylitis

Wet Cupping Therapy in Ankylosing Spondylitis

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

This study evaluates the efficacy of wet cupping therapy in patients with ankylosing spondylitis.Wet cupping therapy will be applied to half of the patients plus routine pharmaceutical treatment while the other half will receive only pharmaceutics

NCT ID: NCT05257174 Enrolling by invitation - Clinical trials for Rheumatoid Arthritis

The Effects of Jing Si Herbal Tea Liquid Packets on Fatigue in Patients With Inflammatory Arthritis

Start date: June 15, 2022
Phase: N/A
Study type: Interventional

Fatigue is a common feature in patients with rheumatic conditions. Fatigue can lead to a decline in physical function, self-confidence, cognitive status, and work performance and significantly impact the quality of life. While pain and inflammation of arthritis can be well controlled nowadays attributed to the advances in anti-rheumatic medications, fatigue remains a challenge. Even with proper therapies for arthritis, the prevalence of severe fatigue is more than 30%, which is a significant burden to both physicians and patients. However, there is no regimen to alleviate fatigue among patients with inflammatory arthritis. Finding a way to combat fatigue will significantly help improve patients' physical and mental state and family society. To investigate the efficacy of Jing Si Herbal Tea Liquid Packets on fatigue in patients with inflammatory arthritis, the investigators propose a two-year research project to recruit approximately 150 patients with fatigue and inflammatory arthritis, including rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis. This project is designed as a randomized, double-blind, placebo-controlled study. The recruited patients will be randomized to receive Jing Si Herbal Tea Liquid Packets or a matching placebo in combination with the background regular anti-rheumatic therapy. The severity of fatigue will be obtained by questionnaire. Clinical parameters, including demographic data and disease activities, will be collected during each visit.

NCT ID: NCT03726645 Enrolling by invitation - Clinical trials for Ankylosing Spondylitis

The Effect of Fecal Microbiota Transplantation in Ankylosing Spondylitis (AS) Patients.

ASGUT
Start date: October 24, 2018
Phase: Early Phase 1
Study type: Interventional

Ankylosing spondylitis (AS) patients often have subclinical gut wall inflammation. Gut dysbiosis has been associated with both AS and Crohn disease, both of which have several features in common. Gut dysbiosis is associated with specific microbial profile in AS patients. Fecal microbiota transplantation (FMT) has been proved to be safe and effective treatment for recurrent Clostridium difficile infection, and the change in gut microbiota is shown to be long lasting. It has led to interest to study its effect on different inflammatory conditions associated with gut dysbiosis. We hypothesize that dysbiosis in AS leads to inflammasome overactivation on gut mucosa. We aim to study the role of gut inflammation, gut microbiota and inflammasome activation in pathogenesis of AS, and the effect of FMT on these factors, as well as clinical activity, in AS patients.

NCT ID: NCT02962479 Enrolling by invitation - Clinical trials for Ankylosing Spondylitis

Is the Human Microbiome Altered in Patients With Axial Spondyloarthritis?

Start date: October 2016
Phase: N/A
Study type: Observational

This study aims to compare biological communities in stool samples obtained from age, diet and BMI-matched subjects in five study groups: subjects with ankylosing spondylitis (AS) never treated with tumor necrosing factor (TNF) inhibitors, subjects with ankylosing spondylitis previously or currently treated with TNF inhibitors, subjects with non-radiographic axial spondyloarthritis (nrSpA) never treated with tumor necrosing factor (TNF) inhibitors, subjects with non-radiographic axial spondyloarthritis previously or currently treated with TNF inhibitors and healthy participants. The differences in fecal microbiota composition will be explored using shotgun metagenomic sequencing through the University of Washington. The investigators predict that this study will confirm a significant difference between the fecal microbiota composition (FMC) of both AS and nrSpA patients and controls.

NCT ID: NCT02260310 Enrolling by invitation - Clinical trials for Ankylosing Spondylitis

The Effect of Acupuncture Protocol Involving in Weizhong (BL4) and Huantiao (GB30) Points in Treating Ankylosing Spondylitis

Start date: October 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of acupuncture protocol involving in Weizhong (BL4) and Huantiao (GB30) points in treating ankylosing spondylitis.

NCT ID: NCT02260284 Enrolling by invitation - Low Back Pain Clinical Trials

The Effect of Acupuncture in Treating Chronic Low-back Pain

Start date: October 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficiency of acupuncture in treating chronic low-back pain

NCT ID: NCT00889694 Enrolling by invitation - Clinical trials for Early Ankylosing Spondylitis

Clinical Study of Tripterygium Capsule to Treat Early Ankylosing Spondylitis

Start date: October 2008
Phase: Phase 2/Phase 3
Study type: Interventional

This study is a 12-week, randomized, placebo and positive drug controlled clinical trial to investigate whether tripterygium capsule is effective and safe in treating patients with ankylosing spondylitis. The investigators expect that the tripterygium capsule is more effective than placebo and has few adverse effects.