Spine Fusion Clinical Trial
Official title:
Postoperative Steroids and Recovery After Spine Fusion
This trial studies how well low-dose postoperative corticosteroids (FDA approved) affect patient outcomes (patient reported outcomes, pain medication use, length of stay, major complications, and time to first bowel movement) after thoracic and/or lumbar spine fusion surgery.
PRIMARY OBJECTIVES This study aims to compare patient outcomes (patient reported outcomes, pain medication use, length of stay, major complications, and time to first bowel movement) between subjects that receive either 20 mg of PO prednisone or 1 mL of 4 mg/mL of IV dexamethasone sodium phosphate and a control group. OUTLINE Participants are patients who elect to participate in the study prior to scheduled thoracic and/or lumbar spine fusion surgery at Oregon Health and Science University. Participants undergo their scheduled spine fusion surgery. After surgery, participants are randomized into either the study drug group or the control (non-treatment) group. If randomized into the study drug group, participants will orally take a daily dose of 20 mg of prednisone (1 mL of 4 mg/mL dexamethasone sodium phosphate if unable to tolerate oral administration) on postoperative days one and two. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04095624 -
Does Preoperative Pain Medication Management Influence Surgical Outcomes in Spinal Fusion
|
N/A | |
| Recruiting |
NCT05367609 -
Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)
|
N/A | |
| Terminated |
NCT03426137 -
Relieving Acute Pain (RAP) Study: A Pilot Study
|
Phase 2 | |
| Active, not recruiting |
NCT04629807 -
Anterior Gen Plus Study
|
N/A | |
| Active, not recruiting |
NCT04379921 -
Improving Spine Surgical Care With Real-Time Objective Patient Tracking Using the Apple Watch
|
N/A | |
| Completed |
NCT02280187 -
InductOs® in Real World Spine Surgery; A Retrospective, French, Multi-centric, Study
|
N/A | |
| Completed |
NCT06082245 -
TLIP Block and ESP Block For Perioperative Analgesia In Patients With Lumbar Spine Fusion Surgery
|
N/A | |
| Recruiting |
NCT06102681 -
Examination of the Effect of Early Mobilization on Postoperative Recovery, Pain, Quality of Life and Complication Development in Elective Minimally Invasive Spine Surgery
|
N/A | |
| Recruiting |
NCT06059820 -
Effectiveness of Conservative Treatment in Patients With Thoracic and Lumbar Fractures Without Neurological Deficit
|
||
| Active, not recruiting |
NCT05001893 -
Clinical Safety and Efficacy of S53P4 Bioactive Glass Putty in Spinal Fusion Surgery
|
||
| Completed |
NCT04711668 -
Effect of Introperative Ketamine and Lidocaine Infusion on Postoperative Opioid Consumption in Posterior Spinal Fusion Surgery
|
N/A | |
| Not yet recruiting |
NCT05850468 -
Effectiveness of Combining Erector Spinea Block With Non Opioid Infusions as Opioid Free Anesthesia in Spine Surgeries.
|
N/A | |
| Completed |
NCT04682418 -
Pedicle Screw Placement With XVS
|
N/A | |
| Not yet recruiting |
NCT04679844 -
Post Marketing Study of MagnetOs Putty Compared to Demineralized Bone Matrix (DBM) Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion
|
N/A | |
| Not yet recruiting |
NCT06393530 -
Erector Spinae Plane Block for Cervical Spine Surgery
|
Phase 4 | |
| Completed |
NCT05401526 -
Fluid Responsiveness in Prone Position
|
||
| Not yet recruiting |
NCT05037968 -
MagnetOs Flex Matrix Compared to Cell Based Allografts in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
|
N/A | |
| Not yet recruiting |
NCT06450834 -
Ostene in Thoracolumbar Decompression and Fusion Evaluated With VIBE
|
||
| Not yet recruiting |
NCT05691062 -
Titanium vs. PEEK Fusion Devices in 1 Level TLIF
|
Phase 4 | |
| Recruiting |
NCT04839783 -
Single Position Spine Surgery Registry
|