Spinal Surgery Clinical Trial
Official title:
A Phase 3b, Open-Label, Single-Group Immunogenicity and Safety Study of Topical Recombinant Thrombin (rThrombin) in Surgical Hemostasis
The purpose of this study is to evaluate the safety and immune system response to recombinant thrombin when used to control bleeding in spinal and vascular surgery.
This is a Phase 3b, open-label, single-group, multisite safety and immunogenicity study of recombinant thrombin (rThrombin) in participants who are at least 18 years of age and undergoing spinal or vascular surgery. Eligible participants will receive topical rThrombin during surgery and complete a 1-month follow-up visit. ;
Allocation: Non-Randomized, Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05023850 -
Comparing Thoracolumbar Interfascial Plane Block With Erector Spinae Plane Block
|
N/A | |
Completed |
NCT01251042 -
Comparison Between Return and Wastage of Your Own Blood, Collected During Spinal Surgery, for Verification of Safety When Returning Blood
|
N/A | |
Completed |
NCT01356082 -
CNAP™ Monitor Study
|
N/A | |
Completed |
NCT06323694 -
Quality of Life, Expectations, Thoughts and Fears of Patients on the Waiting List for Spinal Surgery
|
||
Recruiting |
NCT04370951 -
Efficacy of the Erector Spinae Plane Block in Posterior Thoraco- Lumbar Spinal Decompression Surgery
|
N/A | |
Completed |
NCT03069794 -
Effect of Spinal Surgery on the Posture and the Balance of the Patients Reached of Spinal Pathologies
|
N/A | |
Recruiting |
NCT02595788 -
Haemodynamic Changes During Anaesthesia in the Prone Position, Evaluated Using Transoesophageal Ultrasound
|
N/A | |
Completed |
NCT01855542 -
The Aim of This Investigation is to Compare the Influence of 0.9% Saline and Plasmalyte Solution on Acid-base Balance and Electrolytes in Healthy Patients Undergoing Major Spine Surgeries.
|
N/A | |
Not yet recruiting |
NCT01299818 -
Assessment of Central Pain in Patients Who Undergo Spinal Surgery and Influence in Surgery Outcome
|
N/A | |
Recruiting |
NCT05417100 -
Understanding How Methadone Treatment During Surgery Affects Pain Levels and the Need for Pain Medications After Surgery
|
Phase 3 | |
Terminated |
NCT03160170 -
Efficacy of Suction Enabled Retraction Device
|
N/A | |
Not yet recruiting |
NCT06466083 -
Correlation Analysis of POD and PND in Elderly Spinal Surgery Patients Based on Rs-fMRI
|
||
Recruiting |
NCT06451627 -
Esketamine on Postoperative Sleep Disturbance of Patients Undergoing Spinal Surgery
|
N/A | |
Not yet recruiting |
NCT04922359 -
Effect of Perioperative Lidocaine on Gastrointestinal Function Recovery After Lumbar Spine Surgery in Adults
|
N/A | |
Recruiting |
NCT04189172 -
MiDura-Study (Neuro-Patch in Duraplasty)
|
||
Recruiting |
NCT05553028 -
Study Comparing Arthrodesis Technique of Thoracic and/or Lumbar Spine by Posterior Approach Performed by Robot-assisted Surgery (Robot Mazor X Stealth ™) Versus Conventional Surgery
|
N/A | |
Completed |
NCT02892617 -
Evaluation of the Prevalence of Germs Slow Growth in the Intervertebral Disc (IVD) During Spinal Surgery
|
N/A | |
Completed |
NCT06118489 -
Effects of Different Anesthetic Gases on Hemodynamics, Arterial Oxygenation and Lung Mechanics
|
||
Recruiting |
NCT03512379 -
Clinical Trial for the Application of Robotic System in Spinal Surgery
|
N/A | |
Recruiting |
NCT03501810 -
Study Assessing Safety and Performance of OrtoWell Distractor in Patients Undergoing Spinal Surgery
|