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Spinal Fractures clinical trials

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NCT ID: NCT01817933 Completed - Hip Fractures Clinical Trials

Integrated Rehabilitation Program for Fractures

Start date: July 2010
Phase: N/A
Study type: Interventional

The recovery of range of motion and muscle power after surgical intervention of the fracture will mostly affect patient's daily activities. So postoperative rehabilitation program will play the important role. Correct and effective physical therapy will reduce the functional impairment of limbs after long term casting or surgical fixation, and accelerate to recover the independent daily activities. There is no consensus between immediate or delay and the duration of continue physical therapy will improve the shoulder function、muscle power and degree of satisfaction( physiological function、social function、mental health、 pain、 general health status ) after surgical fixation of fractures. This study will evaluate the patients of the fracture that including of the humeral neck fracture, vertebral fracture, distal radial fracture and hip fractures after surgical fixation, to see the difference of fracture healing time, function recovery and pain sensation after intervention of physical therapy at different time point. From this study, we hope to discriminate the timing of intervention and duration of physical therapy which is the key factors for postoperative prognosis of fractures fixation, and to set up the perfect rehabilitation program in ChangHua Christian Hospital. The results of this study will improve the discomfort of fracture patient's recovery or reduce the complications rate, and set up the standard treatment policy of our hospital , also was the model of other hospitals.

NCT ID: NCT01761084 Completed - Clinical trials for Osteoporotic Fractures

Build Better Bones With Exercise

B3E
Start date: January 2013
Phase: N/A
Study type: Interventional

The long-term goal of our research team is to conduct a large multicentre study to evaluate whether tailored home exercise can prevent fractures in high-risk individuals. The proposed project will address the feasibility of such a trial, but will also evaluate the effect of exercise on quality of life, posture and many other outcomes important to individuals with vertebral fractures. Physiotherapists will conduct 6 home visits with participants to deliver the intervention (or social visit for controls) using a similar model to previous work by our team and others. The purpose of this pilot study is determining the feasibility of recruitment, retention and adherence of an international multicentre randomized controlled study evaluating the efficacy of thrice-weekly home exercise for one year among women with vertebral fracture. As secondary objectives, the investigators will examine the effects of exercise on function, balance, quality of life, pain, falls and fractures. The primary hypothesis is that the investigators will successfully recruit and retain the target sample, and achieve an adherence rate of 60%.

NCT ID: NCT01709110 Completed - Clinical trials for Postmenopausal Osteoporosis

VERtebral Fracture Treatment Comparisons in Osteoporotic Women

VERO
Start date: October 2012
Phase: Phase 4
Study type: Interventional

The primary purpose of participation in this study is to answer whether teriparatide is superior to risedronate in reducing the occurrence of new vertebral fractures during 24 months of therapy.

NCT ID: NCT01643395 Completed - Clinical trials for Vertebral Compression Fracture

VertebrOpLasty Versus Conservative Treatment in Acute Non Osteoporotic Vertebral Fractures

VOLCANO
Start date: September 2010
Phase: Phase 3
Study type: Interventional

The purpose of this protocol is to prove the efficacy of vertebroplasty in patients suffering from acute non osteoporotic vertebral compression fracture. Vertebroplasty consists in the injection of cement (PMMA) in the damaged vertebral body to prevent further collapse. Our study will compare vertebroplasty versus conservative therapy (brace).

NCT ID: NCT01544933 Completed - Clinical trials for Burst Thoracic Spine Fractures

The Influence of the Ribs on the Gravity of Burst Thoracic Spine Fractures

Start date: February 2011
Phase: N/A
Study type: Observational

The purpose of this study is to analyse the anatomic influence of the ribs related to the incidence and severity of burst spine fractures.

NCT ID: NCT01537770 Completed - Clinical trials for Osteoporotic Fractures

Vertebroplasty Compared With a Sham-procedure for Painful Acute Osteoporotic Vertebral Fractures

VOPE
Start date: February 2012
Phase: Phase 4
Study type: Interventional

The main purpose of this study: - to determine whether vertebroplasty has a pain palliating effect superior to a sham-procedure for acute painful osteoporotic vertebral fractures of the thoracic and lumbar spine. Secondary purposes: - To determine if there are differences in the two methods on preventing forward tilting of the spine and/or shortening of the total height of the spine. - measure if there are differences in change of lung capacity between the two methods

NCT ID: NCT01482793 Completed - Clinical trials for Vertebral Compression Fractures

A Controlled Trial of Vertebroplasty for Acute Painful Osteoporotic Fractures

Start date: November 2011
Phase: N/A
Study type: Interventional

The objective of this study is to gather data regarding the efficacy, safety and cost-effectiveness of percutaneous vertebroplasty in the acute fracture group with fractures less than 6 weeks old. The AVAMAX vertebroplasty kits (Care Fusion) will be used for all vertebroplasties. The primary effectiveness analysis will be based on the number of patients whose numeric rating pain score drops from above 7 out of 10 at baseline to below 4 out of 10 at two weeks post-intervention. Our hypothesis is that the vertebroplasty group will have a significantly larger proportion of patients achieving pain reduction than the control group. A secondary analysis will compare the change in mean pain scores and specific activity related pain scores between the two groups at 3 days, 14 days and at 1, 3 and 6 months. Another secondary effectiveness analysis will include the mean change in the back-pain specific limitation in function as quantified by the Roland Scale at these same data collection time points.

NCT ID: NCT01383616 Completed - Clinical trials for Vertebral Compression Fracture

Unipedicular vs. Bipedicular Kyphoplasty for the Treatment of Osteoporotic Vertebral Fractures

Start date: July 2006
Phase: Phase 4
Study type: Interventional

Balloon kyphoplasty for the treatment of patients with osteoporotic vertebral compression fractures has been shown to be successful in providing acute pain relief, enabling improved function, and restoring of vertebral body height. However, limited prospective data exists in the investigation of unipedicular balloon kyphoplasty as a sufficient alternative to bipedicular balloon kyphoplasty. The purpose of this prospective randomized study was to compare the clinical and radiographic outcomes of unipedicular and bipedicular balloon kyphoplasty.

NCT ID: NCT01266200 Completed - Vertebral Fracture Clinical Trials

Identification of Microcirculation and Inflammation After Posterior Stabilization of the Spine

MicroSpine
Start date: December 2010
Phase: N/A
Study type: Interventional

In this project, with unstable vertebral fractures, the microcirculation of the skin and muscle (O2C,Laser-Doppler/White-light -Spectroscopy and contrast-enhanced sonography) will be evaluated in both conventional and in percutaneous minimally invasive technique (XIA versus Mantis) at the thoracolumbar junction.

NCT ID: NCT01200277 Completed - Osteoporosis Clinical Trials

A Trial of Vertebroplasty for Painful Acute Osteoporotic Vertebral Fractures

VertosIV
Start date: January 2011
Phase: Phase 3
Study type: Interventional

The standard care in patients with a painful osteoporotic vertebral compression fracture (VCF) is conservative therapy. Percutaneous vertebroplasty (PV), is a new minimally invasive technique for pain treatment in which bone cement is injected in the fractured vertebra. Recent RCTs provide conflicting results: two sham-controlled studies show no benefit of PV while an unmasked but controlled RCT found significantly better pain relief after PV at acceptable costs.