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Spinal Cord Neoplasms clinical trials

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NCT ID: NCT03893110 Withdrawn - Spinal Tumor Clinical Trials

Carbon PEEK Versus Titanium Pedicle Screws in the Treatment of Spinal Tumors

Start date: June 27, 2018
Phase: N/A
Study type: Interventional

Radiation therapy is a cornerstone in the treatment of spinal neoplasms as radical resections are often limited anatomically. Frequently, a surgical stabilization with implants is required. However, metallic implants not only make the CT-based planning of a subsequent radiation therapy more difficult, but might also have an uncontrolled dose modulating effect in adjuvant radiotherapy. At the spine, radiation is limited by the effective dose posed to the relatively radiosensitive spinal cord. While metallic implants might result in an inhomogeneous and uncontrollable dose distribution due to the interface effect, the use of new radiolucent implants consisting of carbon/polyether ether ketone (PEEK) might allow a more homogeneous and predictable dose distribution. This study aims to evaluate the potential benefits of the use of carbon/PEEK pedicle screws during adjuvant radiation therapy and follow-up imaging of spinal tumors. 60 patients will randomized 1:1 into either treatment arm (Pedicle System Carbon/PEEK vs. Pedicle System Titanium). The feasibility of planning the radiation therapy will be evaluated. The postoperatively administered total radiation dose is documented. The radiological visualization of the area of interest will be evaluated The surgical outcome is evaluated by fusion rate, implant integrity and anchorage. Patients will be followed up for 12 months according to local standards.

NCT ID: NCT01567787 Withdrawn - Neurofibroma Clinical Trials

Proton Radiation Therapy for Spinal Tumors

NF01
Start date: June 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if Proton Therapy can provide effective and safe treatment for Malignant Peripheral Nerve Sheath Tumors of the spine and Neurofibromas of the spine.

NCT ID: NCT01345903 Withdrawn - Clinical trials for Spinal Bone Metastases

Robotic-Assisted Surgery in Treating Patients With Spine Tumors

Start date: December 2012
Phase: N/A
Study type: Interventional

This pilot clinical trial studies robotic-assisted surgery in treating patients with spine tumors. Robotic-assisted surgery is a less invasive type of surgery for spine tumors and may have fewer side effects and improve recovery