Spinal Cord Injury Clinical Trial
Official title:
A Prospective Randomized Clinical Trial Comparing Incisional Negative Pressure Wound Therapy to Conventional Sterile Dressing in Patients Undergoing Thoracolumbar Posterior Spine Surgery
The purpose of this study is to determine if the use of the Prevena™ System decreases the rate of subcutaneous seroma, superficial wound dehiscence and infection.
Certain risk factors have been identified in patients that may lead to poor wound healing or
infection. Many things have been tried to decrease this risk (more antibiotics, different
types of stitches, etc) but very few have been shown to be of any significant benefit.
The use of a special vacuum dressing called the Prevena™ System, which has received approval
from Health Canada for the management of closed surgical incisions, has been shown to be of
some benefit in hip surgery where wounds are identified as being "at risk." Vacuum dressings
have been used with great success in patients with open wounds and have resulted in fewer
infections and wound related complications. It is thought that if vacuum dressings can be
used in the treatment of existing wounds, then maybe they can be used preventatively before
there is a problem with the wound.
Standard wound care after spine surgery involves a dressing that seals the wound for 72 hours
after surgery and is then changed on a daily basis until the surgical sutures or staples are
ready to be removed. This has been routine for many years.
The purpose of this study is to see if using a vacuum dressing (Prevena™ System) will
decrease the number of infections and/or clinic and hospital visits for wound related issues
compared to using a standard dressing on wounds in patients with risk factors for early wound
infection.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT02574572 -
Autologous Mesenchymal Stem Cells Transplantation in Cervical Chronic and Complete Spinal Cord Injury
|
Phase 1 | |
| Recruiting |
NCT05941819 -
ARC Therapy to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury
|
N/A | |
| Completed |
NCT05265377 -
Safety and Usability of the STELO Exoskeleton in People With Acquired Brain Injury and Spinal Cord Injury
|
N/A | |
| Recruiting |
NCT02331979 -
Improving Bladder Function in SCI by Neuromodulation
|
N/A | |
| Completed |
NCT02777281 -
Safe and Effective Shoulder Exercise Training in Manual Wheelchair Users With SCI
|
N/A | |
| Recruiting |
NCT02978638 -
Electrical Stimulation for Continence After Spinal Cord Injury
|
N/A | |
| Completed |
NCT02161913 -
Comparison of Two Psycho-educational Family Group Interventions for Persons With SCI and Their Caregivers
|
N/A | |
| Completed |
NCT02262234 -
Education Interventions for Self-Management of Pain Post-SCI: A Pilot Study
|
Phase 1/Phase 2 | |
| Withdrawn |
NCT02237547 -
Safety and Feasibility Study of Cell Therapy in Treatment of Spinal Cord Injury
|
Phase 1/Phase 2 | |
| Completed |
NCT01642901 -
Zoledronic Acid in Acute Spinal Cord Injury
|
Phase 3 | |
| Terminated |
NCT02080039 -
Electrical Stimulation of Denervated Muscles After Spinal Cord Injury
|
N/A | |
| Completed |
NCT01884662 -
Virtual Walking for Neuropathic Pain in Spinal Cord Injury
|
N/A | |
| Completed |
NCT01471613 -
Lithium, Cord Blood Cells and the Combination in the Treatment of Acute & Sub-acute Spinal Cord Injury
|
Phase 1/Phase 2 | |
| Terminated |
NCT01433159 -
Comparison of HP011-101 to Standard Care for Stage I-II Pressure Ulcers in Subjects With Spinal Cord Injury
|
Phase 2 | |
| Completed |
NCT01467817 -
Obesity/Overweight in Persons With Early and Chronic Spinal Cord Injury (SCI)
|
N/A | |
| Completed |
NCT02149511 -
Longitudinal Morphometric Changes Following SCI
|
||
| Completed |
NCT01025609 -
Dietary Patterns and Cardiovascular (CVD) Risk in Spinal Cord Injury (SCI) Factors In Individuals With Chronic Spinal Cord Injury
|
||
| Completed |
NCT01086930 -
Early Intensive Hand Rehabilitation After Spinal Cord Injury
|
Phase 3 | |
| Completed |
NCT00663663 -
Telephone Intervention for Pain Study (TIPS)
|
N/A | |
| Terminated |
NCT01005615 -
Patterned Functional Electrical Stimulation (FES) Ergometry of Arm and Shoulder in Individuals With Spinal Cord Injury
|
Phase 1/Phase 2 |