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Spinal Cord Injury clinical trials

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NCT ID: NCT06429631 Enrolling by invitation - Spinal Cord Injury Clinical Trials

The Effect of CIC Education on QOL and Compliance With Mobile Application in Individuals With Spinal Cord Injury.

Start date: September 15, 2023
Phase: N/A
Study type: Interventional

Neurogenic bladder is a condition that occurs due to nerve damage or congenital problems and causes urination disorders. Nowadays, in individuals diagnosed with neurogenic bladder, Clean Intermittent Catheterization is often used to evacuate the urine accumulated in the bladder. Clean Intermittent Catheterization(CIC) is a simple, safe and effective method in which the catheter is placed through the meatus. In this application, the catheter is removed without waiting after urine drainage is achieved. This process is usually performed on its own. Since IC(Intermittent Catheterization) is a procedure performed on the bladder, it may cause some complications. IC application must be performed successfully to prevent or reduce complications. The success of the technique largely depends on patient education and follow-up. Sometimes patients may not be able to come to the hospital for follow-up and feedback after IC training. Innovations are needed to ensure the continuation of distance education so that the education of patients who cannot come to the hospital is not incomplete. The literature includes brochures, videos, websites and some mobile applications for IC training. However, no application has been found that monitors patients' urine amounts. This research was planned to examine the effect of clean intermittent catheterization training given via mobile application to individuals with spinal cord injury on their quality of life and compliance.

NCT ID: NCT06190470 Enrolling by invitation - Spinal Cord Injury Clinical Trials

Effects of Marijuana on Neuropathic Pain and Spasticity in Spinal Cord Injury Patients

Start date: January 2, 2024
Phase: Phase 1
Study type: Interventional

The goal of this clinical trial is to compare effects of marijuana or cannabis on neuropathic pain and spasticity in spinal cord injury patients. The main question is: Does the cannabis product from KhonKaen University reduce neuropathic pain and spasticity in spinal cord injury patients? The research design is a crossover study. The participants will be randomly into 2 groups: group 1 and group 2. The participants received either cannabis or placebo for 2 weeks. After completing treatment, participants were swapped to the other group for 2 weeks, a wash-out period is 2 weeks. The outcome measurements are pain and spasticity.

NCT ID: NCT05921487 Enrolling by invitation - Obesity Clinical Trials

Time Restricted Eating to Mitigate Obesity in Veterans With Spinal Cord Injury

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Spinal cord injury (SCI) causes paralysis and muscle atrophy and leads to weight gain and obesity. Obesity directly contributes to functional impairment and cardiometabolic dysfunction. There is a critical need to reduce the growing prevalence of obesity and cardiometabolic disease after SCI. My overall objective in this project is to gather crucial feasibility data on time restricted eating (TRE), a novel form of intermittent fasting. TRE is a straightforward method to induce weight loss without the need for calorie counting. TRE allows individuals to eat all their daily calories in a time restricted window and fast outside that window. A growing body of literature supports the safety and efficacy of TRE. Given the feasibility, high adherence, and substantial benefits of TRE in able-bodied individuals, it is important to test TRE to determine its feasibility in Veterans with SCI. The investigators will first test this intervention in Veterans with thoracic paraplegia, who are at greatest risk of muscle-joint upper body injury given the need to support body weight during activity. The investigators will determine adherence to a TRE window for 6-weeks duration in a convenience sample of Veterans with thoracic paraplegia and obesity. Based on the expected outcomes of good adherence, this study will lay the groundwork for future work by informing the design of a randomized controlled trial to test the efficacy of TRE to facilitate weight loss and improve function.

NCT ID: NCT02769416 Enrolling by invitation - Clinical trials for Traumatic Brain Injury

The National Center for Testing Treatments in Chronic Spinal Cord and Traumatic Brain Injury

NCTT
Start date: December 2015
Phase:
Study type: Observational [Patient Registry]

The NCTT is a prospective, multicenter, observational research network for subjects with chronic spinal cord and/or chronic traumatic brain injury.

NCT ID: NCT02746978 Enrolling by invitation - Spinal Cord Injury Clinical Trials

A Patient-centered Approach to Successful Community Transition After Catastrophic Injury

Start date: August 2013
Phase: N/A
Study type: Interventional

Shepherd Center is bringing a more patient-centered focus to educational, peer-support, and technology resources offered to patients with spinal cord injury and their families and is evaluating these changes. Approximately 740 patients have provided information about healthcare utilization following inpatient rehabilitation. This information will help Shepherd Center staff follow utilization trends and plan programs targeted at the high-use areas.

NCT ID: NCT02688062 Enrolling by invitation - Spinal Cord Injury Clinical Trials

NeuroRegen Scaffold™ With Bone Marrow Mononuclear Cells Transplantation vs. Intradural Decompression and Adhesiolysis in SCI

Start date: January 2016
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate the efficacy and safety of NeuroRegen Scaffold with bone marrow mononuclear cells (BMMCs) on neurological recovery following chronic and complete spinal cord injury, compared to the treatment of surgical intradural decompression and adhesiolysis only.

NCT ID: NCT02688049 Enrolling by invitation - Spinal Cord Injury Clinical Trials

NeuroRegen Scaffold™ Combined With Stem Cells for Chronic Spinal Cord Injury Repair

Start date: January 2016
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of mesenchymal stem cells or neural stem cells combined with NeuroRegen scaffold transplantation in patients with spinal cord injury.

NCT ID: NCT02602639 Enrolling by invitation - Spinal Cord Injury Clinical Trials

Functional Electrical Stimulation With Rowing as Exercise After Spinal Cord Injury

FES
Start date: October 2015
Phase: N/A
Study type: Interventional

Currently, those with spinal cord injury (SCI) demonstrate increased prevalence of obesity (75%) cardiovascular disease (30 - 50%), type II diabetes (21%) and osteoporosis in the legs (100%) when compared to the general population. It is important to identify the modes and intensities of exercise most likely to generate a reduction in these inactivity-related diseases in this population. Therefore, the main purpose of this pilot research project is to implement and test a form of a spinal cord injury-specific exercise, known as FES rowing (FES: functional electrical stimulation).

NCT ID: NCT02352077 Enrolling by invitation - Spinal Cord Injury Clinical Trials

NeuroRegen Scaffold™ With Stem Cells for Chronic Spinal Cord Injury Repair

Start date: January 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of NeuroRegen scaffold with bone marrow mononuclear cells (BMMCs) or mesenchymal stem cells (MSCs) in patients with chronic spinal cord injury.

NCT ID: NCT01694927 Enrolling by invitation - Spinal Cord Injury Clinical Trials

Autologous Mesenchymal Stem Cells in Spinal Cord Injury (SCI) Patients

MSC-SCI
Start date: January 2012
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the use of autologous expanded mesenchymal stem cells intralesional transplantation as a safe and potentially beneficial treatment for patients with spinal cord injury.