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Spinal Cord Injury Thoracic clinical trials

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NCT ID: NCT06274021 Not yet recruiting - Clinical trials for Spinal Cord Injuries

Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury

Start date: April 1, 2024
Phase: Early Phase 1
Study type: Interventional

People with spinal cord injuries may experience muscle tightness or uncontrollable spasms. This study is being conducted to investigate whether transcutaneous spinal stimulation can improve these symptoms. Transcutaneous spinal stimulation is a non-surgical intervention by applying electrical currents using skin electrodes over the lower back and belly. The investigators want to see how well the intervention of transcutaneous spinal stimulation performs by testing different levels of stimulation pulse rates. Also, transcutaneous spinal stimulation is compared to muscle relaxants such as baclofen and tizanidine, commonly given to people with spinal cord injuries, to reduce muscle stiffness and spasms. By doing this, the investigators hope to discover if transcutaneous spinal stimulation similarly reduces muscle spasms and stiffness or if combining both methods works best. This could help improve treatment options for people with spinal cord injuries in the future.

NCT ID: NCT06104982 Completed - Clinical trials for Spinal Cord Injury Thoracic

The Effect of Superimposed Electrical Stimulation on Sitting Balance, Respiratory Functions, and Abdominal Muscle Thickness in Complete Spinal Cord Injury

Start date: February 6, 2022
Phase: N/A
Study type: Interventional

The primary aim of the current study was to investigate the effects of SiFES (superimposed functional electrical stimulation) on sitting balance in patients with complete Spinal Cord Injury (SCI) compared to exercise alone. Additionally, the study aims to investigate improvements in respiratory functions and changes in abdominal muscle thickness measured by ultrasonography (USG) following SiFES treatment. The fundamental questions that investigators want to answer are as follows: - [question 1]: "Does abdominal SiFES therapy improve sitting balance in patients with complete SCI?" - [question 2]: "Does abdominal SiFES therapy improve respiratory functions in patients with complete SCI?"

NCT ID: NCT01321333 Completed - Spinal Cord Injury Clinical Trials

Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Patients With Thoracic Spinal Cord Injury

Start date: March 2011
Phase: Phase 1/Phase 2
Study type: Interventional

This study will evaluate the effect of single transplantation of HuCNS-SC cells into the thoracic spinal cord of patients with sub-acute spinal cord injury.