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Pain Phenotyping in Patients With Neuropathic Pain After Spinal Cord Injury

Spinal Cord Injuries Clinical Trial

Official title:
Pain Phenotyping in Patients With Neuropathic Pain After Spinal Cord Injury

Clinical Trial Summary

The development of neuropathic pain is one of the most debilitating sequels after a spinal cord injury (SCI). The overall aim of this study is to investigate potential underlying pathophysiological mechanisms of neuropathic pain after SCI. The functionality of the nociceptive pathway in humans as well as its plastic changes following SCI will be inferred with sophisticated sensory and pain phenotyping using quantitative sensory testing (i.e., psychophysical measures), objective neurophysiological measures of pain processing and the recording of pain-related autonomic responses (i.e., galvanic skin response, cardiovascular measures and pupil dilation). In addition, the interplay between the somatosensory and autonomic nervous system and its association with the development and maintenance of neuropathic pain after SCI will be investigated.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06443281
Study type Observational
Source University of Zurich
Contact Michèle Hubli, PD Dr.
Phone +41 44 510 72 03
Email michele.hubli@balgrist.ch
Status Recruiting
Phase
Start date April 17, 2024
Completion date April 30, 2030
View Details
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