Ureteric Jet Doppler Waveforms in Patients With Spinal Cord Injury

Spinal Cord Injuries Clinical Trial

Official title:

The Characteristics of Ureteric Jet Doppler Waveforms and Factors Affecting Them in Patients With Spinal Cord Injury

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05568862
• Other study ID #: ik
• Status: Completed
• Start date: June 17, 2021
• Est. completion date: September 30, 2022

Study information

• Verified date: October 2022
• Source: Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Urinary dysfunction is very common in individuals with spinal cord injury. The urine flowing from the collecting ducts to the renal calyx stretches the calyces. ANS controlled peristaltic contractions originate in the proximal renal pelvis and travel down the ureters, pushing urine from the renal pelvis towards the bladder. The urine bolus delivered from the kidneys through the peristaltic contraction of the ureter creates an image called ureteric jet. Using the Doppler analysis of ureteral jets, previous studies have examined the changes in the ureteric jet pattern in pathological conditions such as the diagnosis of normal ureteral physiology.

Description:

This cross-sectional study was conducted at a tertiary rehabilitation center. Eighteen spinal cord injury patients who met the inclusion criteria and 24 healthy volunteers were included in the study. The appearance of üreteric jet form and bladder wall thicknesses were obtained by urinary Doppler ultrasound both in patient and control groups. Detrusor pressure and bladder volume were measured only in patient group during urodynamic assessment.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 42
• Est. completion date: September 30, 2022
• Est. primary completion date: March 20, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

The case group

Inclusion Criteria:

• With signs of upper motor neuron lesion,

• Suprasacral spinal cord injury,

• Normal urinary ultrasound findings

• Planned urodynamics

Exclusion Criteria:

• Neurological disease other than spinal cord injury

• Urinary tract infection

• Urinary obstruction

• History of urinary tract Stones

• Diabetes, hypertension

• History of urinary surgery,

• Sacral injury

• Second motor neuron lesions (such as cauda equina, or cauda conus)

The control group

Inclusion Criteria:

• Normal urinary ultrasonography

Exclusion Criteria:

• Neurological disease

• Urinary tract infection

• Urinary obstruction

• History of urinary tract Stones

• Diabetes, hypertension

Related Conditions & MeSH terms

• Spinal Cord Injuries
• Wounds and Injuries

Intervention

Diagnostic Test:
• Doppler ultrasound, Urodynamic assessment.
The patients included in the study group were given 600 cc of water in the morning and the Doppler ultrasound was performed 30 minutes later
• Urodynamic assessment.
A transurethral double lumen catheter was used to measure intravesical pressure in the urodynamic unit for the patients in the study group immediately after the use of the Doppler USG

Locations

Country	Name	City	State
Turkey	Gaziler PMR, Training and Research Hospital, Department of PMR	Ankara	Çankaya

Sponsors (1)

Lead Sponsor	Collaborator
Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	doppler USG	The patients included in the study group were given 600 cc of water in the morning and the Doppler USG was performed 30 minutes later	15-30 minute
Primary	Urodynamic assessment.	A transurethral double lumen catheter was used to measure intravesical pressure in the urodynamic unit	30 minute