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Spinal Cord clinical trials

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NCT ID: NCT06204315 Not yet recruiting - Spinal Cord Clinical Trials

Risk Adapted Spinal Cord/Cauda Constraint Relaxation for High-risk Patients With Metastatic Epidural Spinal Cord Compression Undergoing Spine Stereotactic Radiosurgery

Start date: June 30, 2024
Phase: Phase 2
Study type: Interventional

To learn about the safety of a procedure called cord dose escalated spine stereotactic radiosurgery (CDE-SSRS) in patients with MESCC.

NCT ID: NCT05603442 Recruiting - Anesthesia, Local Clinical Trials

Thoracic Intervertebral Foramen Block

Start date: June 7, 2022
Phase: N/A
Study type: Interventional

The investigators hypothesize an alternative way to perform thoracic paravertebral block, by placing the needle tip over and behind the transverse process of vertebra, via the thoracic intervertebral foramen. This anesthetic procedure is called thoracic intervertebral foramen block. The study aims to verify the spread of dye on to the the nervous structures of retropleural space (the ventral rami, the communicating rami, and the sympathetic trunk), and into the thoracic paravertebral space and epidural space. To accomplish this, a prospective cadaveric study was designed.

NCT ID: NCT05544175 Not yet recruiting - Spinal Cord Clinical Trials

NEUROMOdulation Pain Therapy in Combination With Intensive Physiotherapy

NEUROMOFY
Start date: October 1, 2024
Phase: N/A
Study type: Interventional

In this project, the aim is to verify that neuromodulation therapy (spinal cord stimulation) in combination with intensive physiotherapy on a neurophysiological basis will lead to the restoration of mobility of lower limbs.

NCT ID: NCT03207841 Completed - Diabetes Clinical Trials

Low Carbohydrate/High Protein Diet to Improve Metabolic Health

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

Individuals with spinal cord injury (SCI) are living to ages when metabolic disorders are highly prevalent. The combination of impaired glucose tolerance and insulin resistance can disrupt lipid metabolism and increase the risk of cardiovascular disease and diabetes, and contribute to an accelerated aging process in the SCI population. Feasible interventions to improve metabolic function in the chronic SCI are in great demand. Compared to pharmacologic therapies, dietary modification is a more cost-effective treatment option for reducing the risk of metabolic dysfunction that, surprisingly, has not been rigorously investigated in people with SCI. Therefore, in the present study the investigators will investigate the efficacy of an 8-week, eucaloric (a meal plan designed specifically to provide the exact amount of calories needed to maintain a given body weight) LC-HP dietary intervention for improving metabolic function, body composition, gut bacteria composition and quality of life in individuals with SCI and impaired glucose tolerance or type 2 diabetes. The investigators also aim to determine the association between changes in the composition of gut bacteria and improvements in metabolic function and the association between improvements in metabolic function and improvements in quality of life.

NCT ID: NCT02415244 Completed - Epidural Clinical Trials

Transesophageal Echocardiography (TEE): A Novel Technique for Spinal Cord Imaging

Start date: July 2012
Phase:
Study type: Observational

The aim of this prospective observational study is to assess whether transesophageal echocardiography (TEE) can be used to identify the structures within the vertebral foramen of the spinal column and to determine the range of spinal segments which can be visualized.