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Spinal Anesthesia clinical trials

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NCT ID: NCT05133271 Recruiting - Spinal Anesthesia Clinical Trials

Prediction of Maternal Arterial Hypotension After Spinal Anesthesia by Passive Leg Raise Test.

EDLIDL
Start date: February 3, 2021
Phase: N/A
Study type: Interventional

Spinal anesthesia for cesarean section is associated with a high incidence of low blood pressure. However, the pathophysiology of this arterial hypotension is not unequivocal and could involve, in addition to drug vasoplegia, a mechanical cause linked to lower caval compression or even true or relative hypovolemia. Passive leg raise test has been proposed in an attempt to identify parturients who are more likely to develop low blood pressure after spinal anesthesia. Nevertheless, the data available on this volume expansion test to predict hemodynamic variations after performing spinal anesthesia are still limited and few objective criteria have been described to predict this arterial hypotension. The objective of the research is to study the hypothesis according to which the presence of hypovolaemia (true or relative) objectified by a positive passive leg raise test would cause hypotension more frequent and more marked in intensity.

NCT ID: NCT05002257 Recruiting - Spinal Anesthesia Clinical Trials

Impact of Listening to Music on Anxiety Postoperative in a Postanesthesic Care Unit (PACU) After Spinal Anesthesia

MusicAnx-SSPI
Start date: May 25, 2021
Phase: N/A
Study type: Interventional

Our hypothesis is that listening to music has a beneficial effect on the French population receiving spinal anesthesia for a scheduled procedure. We think we can reduce anxiety when switching to SSPI, using creative music therapy software (Music Care) French validated by clinical research.

NCT ID: NCT04598061 Recruiting - Spinal Anesthesia Clinical Trials

IV Dexmedetomidine as Spinal Anesthesia Adjuvant in Infants

RACHI_dex
Start date: October 1, 2020
Phase:
Study type: Observational

- Spinal anesthesia in newborns is one of " Gold standard " techniques in short subumbilical surgeries (less than 30 minutes) with advantage of avoiding the risks inherent to general anesthesia. - Spinal anesthesia of the newborn remains a complex technical procedure with a failure rate of up to 16%. The child's movements and certain degrees of discomfort may also interfere with the successful completion of the procedure. - The second major issue of spinal anesthesia is the limitation of the motor block duration and the need for general anesthesia to complete the surgery - Spinal anesthesia duration can be prolonged by the addition of differents adjuvant such as opioid or alpha 2 adrenergic agonist. - Since 2018, dexmedetomidine, an alpha 2 adrenergic agonist with sedative, analgesic and anxiolytic properties, is being used as a current and standard practice in our anesthesia department. Intravenous administrationis performed ten to twenty minutes before spinal anesthesia placement in all children weighing less than 7 kg undergoing an infra-umbilical surgery of expected duration of less than 1 hour. This strategy ensures the child's comfort and allows the procedure to be performed under optimal conditions for practitionner. - The objective of this study is to review our practices and to evaluate the impact of the use of dexmedetomidine during spinal anesthesia of newborns and infants.

NCT ID: NCT04592926 Recruiting - Cesarean Section Clinical Trials

Pre-Insertion Ultrasound for Lateral-Position Spinal in Cesarean Delivery

Start date: April 22, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the impact of lumbar ultrasound anatomic mapping using the Accuro device on the number of needle redirections, when performing spinal anesthesia in the lateral decubitus position on patients undergoing elective cesarean delivery.

NCT ID: NCT03883763 Recruiting - Spinal Anesthesia Clinical Trials

Hyperbaric Novabupi® in Spinal Anesthesia in Lower Limbs Vascular Surgery

Start date: April 1, 2022
Phase: Phase 3
Study type: Interventional

This is a multicenter, randomized, double-blind, active-controlled study to evaluate the non-inferiority of hyperbaric Novabupi® versus hyperbaric Neocaine® in spinal anesthesia in lower limbs vascular surgery. The schedule consists of four visits: screening (visit 1); pre-anesthetic evaluation and randomization (visit 2); treatment (visit 3) and discharge from study (visit 4).

NCT ID: NCT03248817 Recruiting - Clinical trials for Cesarean Section Complications

Phenylephrine Infusion in Cesarean Delivery

Start date: September 28, 2017
Phase: Phase 4
Study type: Interventional

the investigators will compare variable infusion of phenylephrine (at a starting rate of 0.75 mcg/Kg/min) with fixed rate (0.75 mcg/Kg/min which will stop of reactive hypertension occurred) and single shot (1.5 mcg/Kg) phenylephrine

NCT ID: NCT03248791 Recruiting - Clinical trials for Cesarean Section Complications

Vasopressor Infusion in Cesarean Delivery

Start date: August 20, 2017
Phase: Phase 4
Study type: Interventional

Comparison will be conducted between continuous variable infusions of both drugs (Phenylephrine and Norepinephrine) with starting doses of 0.75 mcg/Kg/min and 0.1 mcg/Kg/min respectively for prophylaxis against Post-spinal hypotension during cesarean delivery.

NCT ID: NCT02987192 Recruiting - Spinal Anesthesia Clinical Trials

Minimally Invasive Lumbar Aneasthesia Used for Cesarean Section

Start date: November 2016
Phase: N/A
Study type: Interventional

Spinal canal anesthesia is marked the most commonly used method of cesarean section. Traditional spinal anesthesia may cause post-dural puncture headache and low back pain.Plenty of parturients are undergoing anticoagulation therapy.They may be forced to accept general anesthesia in order to avoid epidural hematoma.Therefore, we propose minimally invasive spinal anesthesia.

NCT ID: NCT02937792 Recruiting - Spinal Anesthesia Clinical Trials

Large Volume Bupivacaine 0.5% Versus Small Volume in Elective Caesarean Section

Start date: October 2016
Phase: N/A
Study type: Interventional

To test the safety of high dose spinal in elective CS after prolonged sitting position.

NCT ID: NCT01415284 Recruiting - Hypotension Clinical Trials

ED50 Determination of Hydroxyethylstarch for Treatment of Hypotension During Cesarean Section Under Spinal Anesthesia

Start date: October 2011
Phase: Phase 4
Study type: Interventional

The purpose of this trial is to determine the effective volume of hydroxyethylstarch 130/0.4 which would prevent the occurence of maternal hypotension in 50% of healthy pregnant women undergoing a cesarean section under spinal anesthesia.