Neuromuscular Diseases Clinical Trial
Official title:
Metformin in Children With Motor Deficit
Obesity with insulin resistance in the paediatric population provides an increasing challenge. Children with neurological or neuromuscular diseases are even more prone to obesity: their locomotor impairment leads to an increasingly sedentary lifestyle, a decrease in physical fitness and an increase in body fat (1-3). Obesity, in turn, can be associated with a decrease in physical fitness and a further increase in body fat. In this study we want to evaluate the effect of an insulin-sensitizer, metformin, in a group of overweight/obese patients with neurological or neuromuscular diseases. Metformin is a well-established insulin sensitizer.
Obesity with insulin resistance in the paediatric population provides an increasing challenge. Children with neurological or neuromuscular diseases are even more prone to obesity: their locomotor impairment leads to an increasingly sedentary lifestyle, a decrease in physical fitness and an increase in body fat (1-3). Obesity, in turn, can be associated with a decrease in physical fitness and a further increase in body fat. In this study we want to evaluate the effect of an insulin-sensitizer, metformin, in a group of overweight/obese patients with neurological or neuromuscular diseases. Metformin is a well-established insulin sensitizer. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT03548779 -
North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2
|
N/A | |
| Completed |
NCT04435093 -
Digitalization Playful Module of Motor Function Measure Assessment for Children With Neuromuscular Disorders, MFM-Play Pilot Study.
|
||
| Not yet recruiting |
NCT04089696 -
Validation of the "ExSpiron©" in Patients With ALS
|
N/A | |
| Not yet recruiting |
NCT05785546 -
Elaboration of a Pronostic Score of Changes on Wheelchair's Seating System
|
||
| Completed |
NCT01313325 -
Hippotherapy to Improve the Balance of Children With Movement Disorders
|
N/A | |
| Recruiting |
NCT04098094 -
Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases
|
||
| Active, not recruiting |
NCT05070624 -
The Peer Support Study
|
N/A | |
| Completed |
NCT04729920 -
Home Use of Mechanical Insufflation/Exsufflation Devices in Neuromuscular Diseases
|
||
| Recruiting |
NCT04581577 -
Perceptions of the Clinical and Psychosocial Impact of Covid-19 in Patients With Neuromuscular and Neurological Disorders
|
||
| Completed |
NCT06428864 -
Effect of the Use of a 3D Scanner Application on a Smartphone to Mold Garchois Orthotic Device in Neuromuscular Diseases Patients With Scoliosis
|
||
| Enrolling by invitation |
NCT05539456 -
Reliability and Validity of the Turkish Version of the PedsQL 3.0 Neuromuscular Module for 2-to 4- Year-old
|
||
| Completed |
NCT05353738 -
Efficacy of Vaccination Against COVID-19 in Patients Presenting a Neuromuscular Disease With Severe Amyotrophy
|
||
| Recruiting |
NCT04541602 -
Detection of Neuromuscular Complications in Critically Ill Patients
|
||
| Completed |
NCT03394859 -
Electronic Medical Records and Genomics (eMERGE) Phase III
|
||
| Enrolling by invitation |
NCT05099107 -
Changes of Motor Function Tests in Congenital Myopathy Subjects Treated With Oral Salbutamol as Compared to no Treatment
|
N/A | |
| Completed |
NCT05070910 -
NDT Effectiveness Study
|
N/A | |
| Recruiting |
NCT04100993 -
Multisystem and Autonomic Complications of NMD on Long-term NIV
|
||
| Recruiting |
NCT04986059 -
Effects of Pre-event Massage on Muscle Activity
|
N/A | |
| Completed |
NCT01022931 -
Epidemiology and Clinical Presentation of H1N1 Infection in Children in Geneva
|
N/A | |
| Terminated |
NCT03353064 -
Telemedicine for Improving Outcome in Inner City Patient Population With Hypercapneic Respiratory Failure
|
N/A |