Speech Clinical Trial - Sensory Memory in Speech Motor Learning

Status Recruiting

Clinical Trial Summary

The proposed studies focus on memory for speech movements and sounds and its relation to learning. Continuous theta-burst transcranial magnetic stimulation (cTBS) will be used to suppress activity in a region of pre-frontal cortex associated with somatic and auditory working memory (Brodmann area 46v) to test its involvement in learning.

Clinical Trial Description

This study will assess the relationship between sensory working memory and speech motor adaptation using a between subjects design. Participants will be assigned to one of two groups. Each group will undergo both auditory and somatosensory working memory tests. This will be followed by adaptation to altered auditory feedback. Using a different group of subjects, cTBS will be used to disrupt neural activity in Brodmann area 46v in ventrolateral prefrontal cortex to test its involvement in adaptation. One set of tests will focus on the effects of cTBS on both auditory and somatosensory working memory. A second set of tests will focus on the effects of cTBS on speech motor adaptation to altered auditory feedback. Both working memory and adaptation are assessed on 0 to 100 scales. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04818268
Study type	Interventional
Source	Yale University
Contact	David Ostry
Phone	2038656163
Email	david.ostry@yale.edu
Status	Recruiting
Phase	N/A
Start date	August 1, 2019
Completion date	July 31, 2025

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