Speech Sound Disorder Clinical Trial
Official title:
Manipulating Linguistic Complexity to Improve Child Language Treatment Outcomes
Verified date | March 2023 |
Source | San Diego State University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Phonological disorder (PD) and specific language impairment (SLI) directly impact a child's ability to communicate and are among the most prevalent developmental disorders. The proposed experiments manipulate the complexity of treatment targets to identify the most efficacious treatment approaches for English- and Spanish-speaking children aged 3 to 6 years who present with these disorders. This research will reveal the nature of interactions between sound and structure in language for these children and will have significant implications for a unique approach to target selection when treating persistent phonological and grammatical difficulties in children with PD, SLI, or both.
Status | Completed |
Enrollment | 41 |
Est. completion date | December 31, 2021 |
Est. primary completion date | December 31, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 3 Years to 6 Years |
Eligibility | Participants will be recruited through announcements to schools and community organizations. Data will include caregiver-reported demographic data, scores on the standardized tests, digital recordings of subjects' spontaneous language, treatment probes and generalization probes, computerized analyses of speech/language samples and probes, and transcribed responses from speech/language samples and probes. All such data will be collected following caregiver consent and child assent. Further, all data will be collected at the SDSU clinic, with the exception of the caregiver report, which may be completed by the caregiver at home. Screening procedures will include administration of the following: - Caregiver report of child history and language background, binaural hearing screening, - Goldman-Fristoe Test of Articulation 3 (GFTA3; English) or Bilingual English-Spanish Assessment (BESA; Spanish), - Preschool Language Scales (PLS; English or Spanish), - Leiter-R, spontaneous language sample, and - Protocol for the Assessment of English Phonotactics (PEEP; English) or Assessment of Spanish Phonology (ASP; Spanish). Children who meet the inclusionary criteria below will be classified as having PD, SLI, or PD-SLI, per those criteria. INCLUSIONARY CRITERIA: All participating children must meet the following inclusionary criteria: - between the ages of 3 and 6 years of age; - speak Spanish (Experiment 1) or English (Experiments 2 and 3); - present with phonological disorder (PD, n = 22), specific language impairment (SLI, n = 6), or co-occurring PD-SLI (n = 18) (see below for additional criteria for inclusion). The research program will over-recruit at 60 children, to reach the desired 46 participants. Participants will complete a battery of assessment measures. Information gleaned from these measures will be used to further determine eligibility for the proposed study, which include both quantitative and qualitative criteria. Specifically, all PD (Experiments 1 and 2) and PD-SLI (Experiment 2 and 3) participants must: - exhibit 5 or more sounds in error across three or more speech sound manner classes; - score = 1.5 standard deviations below the mean on the GFTA3, if English-speaking; - score = 1.5 standard deviations below the mean on the Phonology subtest of the BESA, if Spanish-speaking; and - exhibit = 20% accuracy on consonants and clusters independent of tense morphemes. Moreover, all SLI (Experiment 3) and PD-SLI (Experiments 2 and 3) participants must: - score = 1 standard deviation below the mean on the Preschool Language Scales (PLS), a test of expressive and receptive language; and - exhibit a mean length of utterance (MLU) = 1 standard deviation below the mean for age- and demographic-matched peers, based on a language sample. EXCLUSIONARY CRITERIA: All participants (Experiments 1, 2, and 3) must: - not be receiving speech/language services elsewhere; - pass a binaural hearing screening at 20 decibels; - achieve score above a standard score of 70 on a test of nonverbal cognition (Leiter-R); and - have typical intellectual, hearing, social-emotional, and neurological development, per parent report. In addition, to rule out concomitant difficulty in other domains of language all PD participants (Experiments 1 and 2) must: - score > 1 standard deviation below the mean on the PLS, if English-speaking; - have an MLU > 1 standard deviation below the mean for age- and demographic-matched peers, based on a language sample. To rule out concomitant difficulty in phonology, the SLI participants (Experiment 3) must: - score > 1.5 standard deviations below the mean on the GFTA3; and - exhibit fewer than 5 sounds in error and > 20% accuracy on final consonants and clusters independent of tense morphemes. If the above criteria are not met, a child will be excluded from participation. |
Country | Name | City | State |
---|---|---|---|
United States | San Diego State University Speech-Language Clinic | San Diego | California |
Lead Sponsor | Collaborator |
---|---|
San Diego State University | National Institute on Deafness and Other Communication Disorders (NIDCD) |
United States,
Barlow JA. Phonological change and the representation of consonant clusters in Spanish: a case study. Clin Linguist Phon. 2005 Dec;19(8):659-79. doi: 10.1080/02699200412331279794. — View Citation
Combiths PN, Barlow JA, Potapova I, Pruitt-Lord S. Influences of Phonological Context on Tense Marking in Spanish-English Dual Language Learners. J Speech Lang Hear Res. 2017 Aug 16;60(8):2199-2216. doi: 10.1044/2017_JSLHR-L-16-0402. — View Citation
Cummings AE, Barlow JA. A comparison of word lexicality in the treatment of speech sound disorders. Clin Linguist Phon. 2011 Apr;25(4):265-86. doi: 10.3109/02699206.2010.528822. Epub 2010 Dec 15. — View Citation
Gierut JA, Champion AH. Syllable onsets II: three-element clusters in phonological treatment. J Speech Lang Hear Res. 2001 Aug;44(4):886-904. doi: 10.1044/1092-4388(2001/071). — View Citation
Gierut JA, Morrisette ML, Dickinson SL. Effect Size for Single-Subject Design in Phonological Treatment. J Speech Lang Hear Res. 2015 Oct;58(5):1464-81. doi: 10.1044/2015_JSLHR-S-14-0299. — View Citation
Gierut JA, Morrisette ML. Age of word acquisition effects in treatment of children with phonological delays. Appl Psycholinguist. 2012 Jan 1;33(1):121-144. doi: 10.1017/S0142716411000294. — View Citation
Gierut JA, Morrisette ML. Effect size in clinical phonology. Clin Linguist Phon. 2011 Nov;25(11-12):975-80. doi: 10.3109/02699206.2011.601392. Epub 2011 Jul 25. — View Citation
Gierut JA. Complexity in Phonological Treatment: Clinical Factors. Lang Speech Hear Serv Sch. 2001 Oct 1;32(4):229-241. doi: 10.1044/0161-1461(2001/021). — View Citation
Gierut JA. Nexus to Lexis: Phonological Disorders in Children. Semin Speech Lang. 2016 Nov;37(4):280-290. doi: 10.1055/s-0036-1587704. Epub 2016 Oct 4. — View Citation
Gierut JA. Phonological complexity and language learnability. Am J Speech Lang Pathol. 2007 Feb;16(1):6-17. doi: 10.1044/1058-0360(2007/003). — View Citation
Gierut JA. Syllable onsets: clusters and adjuncts in acquisition. J Speech Lang Hear Res. 1999 Jun;42(3):708-26. doi: 10.1044/jslhr.4203.708. — View Citation
Leonard LB, Davis J, Deevy P. Phonotactic probability and past tense use by children with specific language impairment and their typically developing peers. Clin Linguist Phon. 2007 Oct;21(10):747-58. doi: 10.1080/02699200701495473. — View Citation
Leonard LB, Deevy P. The Changing View of Input in the Treatment of Children With Grammatical Deficits. Am J Speech Lang Pathol. 2017 Aug 15;26(3):1030-1041. doi: 10.1044/2017_AJSLP-16-0095. — View Citation
Pater J, Barlow JA. Constraint conflict in cluster reduction. J Child Lang. 2003 Aug;30(3):487-526. — View Citation
Plante E, Ogilvie T, Vance R, Aguilar JM, Dailey NS, Meyers C, Lieser AM, Burton R. Variability in the language input to children enhances learning in a treatment context. Am J Speech Lang Pathol. 2014 Nov;23(4):530-45. doi: 10.1044/2014_AJSLP-13-0038. — View Citation
Potapova I, Kelly S, Combiths PN, Pruitt-Lord SL. Evaluating English Morpheme Accuracy, Diversity, and Productivity Measures in Language Samples of Developing Bilinguals. Lang Speech Hear Serv Sch. 2018 Apr 5;49(2):260-276. doi: 10.1044/2017_LSHSS-17-0026. — View Citation
Pruitt S, Oetting J. Past tense marking by African American English-speaking children reared in poverty. J Speech Lang Hear Res. 2009 Feb;52(1):2-15. doi: 10.1044/1092-4388(2008/07-0176). Epub 2008 Aug 11. — View Citation
Thompson CK, Shapiro LP. Complexity in treatment of syntactic deficits. Am J Speech Lang Pathol. 2007 Feb;16(1):30-42. doi: 10.1044/1058-0360(2007/005). — View Citation
Thompson CK. Complexity in language learning and treatment. Am J Speech Lang Pathol. 2007 Feb;16(1):3-5. doi: 10.1044/1058-0360(2007/002). — View Citation
Van Horne AJO, Fey M, Curran M. Do the Hard Things First: A Randomized Controlled Trial Testing the Effects of Exemplar Selection on Generalization Following Therapy for Grammatical Morphology. J Speech Lang Hear Res. 2017 Sep 18;60(9):2569-2588. doi: 10.1044/2017_JSLHR-L-17-0001. — View Citation
* Note: There are 20 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Treatment Probe Accuracy Change | The Treatment Probe is made of the selected treatment stimuli (words) that are consistent with the child's assigned experimental condition, and evaluates production accuracy of the treatment target within the verb stimuli. The treatment targets in these words have a consonant singleton or consonant cluster ("tee" vs. "tree", "sees" vs. "seats"), and are mono- or bi-morphemic contexts ("tease" vs. "sees"). Children are asked to pronounce each word following presentation of a corresponding picture and a verbal prompt. The Treatment Probe allows us to track the effectiveness of treatment on the target consonant or consonant cluster in the treated stimuli. Accuracy of the consonant or consonant cluster is binary, as 'incorrect' (e.g., "tee" for target "tree") or 'correct' (e.g., "tree" for target "tree"). | Change in percentage of consonant or consonant cluster accuracy (depending on Arm/Group) from first treatment session to final treatment session; up to 6 weeks. | |
Primary | Generalization Probe Accuracy Change | The Generalization Probe consists of words and phrases that target each consonant, cluster, and morpho-syntactic constructs a minimum of 10 times across relevant contexts (i.e., word- and utterance-position). The Generalization Probe allows us to track the effects of treatment (generalization) to untreated stimuli and to monitor control variables by measuring production accuracy of stimuli. The Generalization Probe samples each consonant and consonant cluster of the target language across multiple words and contexts. Children are asked to pronounce each word following presentation of a corresponding picture and a verbal prompt. Accuracy of the consonant or consonant cluster is binary, as 'incorrect' (e.g., "tee" for target "see") or 'correct' (e.g., "see" for target "see"). | Change in percent consonant accuracy from baseline to immediately following final treatment session; up to 6 weeks. |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04117360 -
Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses
|
||
Completed |
NCT04625062 -
Comparing Traditional and Biofeedback Telepractice Treatment for Residual Speech Errors
|
Phase 1 | |
Completed |
NCT06075303 -
Dynamic Assessment of Phonological Disorders
|
N/A | |
Recruiting |
NCT05929859 -
Intensive Speech Motor Chaining Treatment for Residual Speech Sound Disorders
|
N/A | |
Recruiting |
NCT06366256 -
Simplified Ultrasound Feedback for Speech Remediation
|
N/A | |
Recruiting |
NCT03700151 -
Efficacy of an Intervention for the Children With Severe Speech Sounds Disorders
|
N/A | |
Not yet recruiting |
NCT06416306 -
Treatment Targets in Spanish and English Bilingual Speech Intervention
|
Phase 1 | |
Withdrawn |
NCT03972449 -
Beatboxing and Residual Speech Errors
|
N/A | |
Completed |
NCT03538925 -
Building Sentences With Preschoolers Who Use AAC
|
Phase 2 | |
Withdrawn |
NCT03006744 -
Sharing Books With Children
|
N/A | |
Recruiting |
NCT05988515 -
AI-Assisted Treatment for Residual Speech Sound Disorders
|
N/A | |
Recruiting |
NCT03737318 -
Correcting Residual Errors With Spectral, Ultrasound, Traditional Speech Therapy
|
Phase 2 | |
Completed |
NCT03736213 -
Delineation of Sensorimotor Subtypes Underlying Residual Speech Errors
|
Phase 1 | |
Completed |
NCT03663972 -
Age-related Correlates of Treatment for Late-acquired Sounds
|
N/A | |
Recruiting |
NCT04858035 -
Auditory-Perceptual Training Via Telepractice
|
Phase 1 | |
Recruiting |
NCT04858022 -
Visual Acoustic Biofeedback for RSE Via Telepractice
|
Phase 2 | |
Withdrawn |
NCT03972891 -
Influence - Intervention Break - Children - Speech Sound Disorders
|
N/A | |
Recruiting |
NCT04558541 -
A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In DLD: Production
|
N/A | |
Recruiting |
NCT04996472 -
A Framework For Linking Sequential Pattern Rules in DLD: Perception in Adults
|
N/A | |
Recruiting |
NCT04531514 -
A Framework For Linking Sequential Pattern Rules in DLD: Perception in Toddlers
|
N/A |