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Exposure, D-cycloserine Enhancement, and Functional Magnetic Resonance Imaging (fMRI) in Snake Phobics

Specific Phobia Clinical Trial

Official title:
Exposure, D-cycloserine Enhancement, and Functional Magnetic Resonance Imaging (fMRI) in Snake Phobics

Clinical Trial Summary

The aim of the present study is to determine whether people receiving d-cycloserine and exposure therapy show different brain reactions to symptom provocation compared to people receiving placebo and exposure therapy.

Clinical Trial Description

D-cycloserine (DCS) is a partial N-methyl-D-aspartate (NMDA) receptor agonist that may improve or accelerate extinction learning. We will randomly assign people with snake phobia to receive DCS or placebo, and then provide all participants with exposure therapy. We will examine whether people receiving DCS and vs. placebo show different brain reactions to symptom provocation before and after exposure therapy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01450306
Study type Interventional
Source Hartford Hospital
Contact
Status Completed
Phase N/A
Start date July 2010
Completion date December 2011
View Details
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