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Solitary Pulmonary Nodule clinical trials

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NCT ID: NCT02832284 Completed - Clinical trials for Solitary Pulmonary Nodule

iNod System Human Feasibility Assessment

iNod
Start date: January 18, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to demonstrate feasibility to access, visualize, and obtain specimens adequate for cytology of lung lesions in subjects with suspected lung cancer when using the iNod System.

NCT ID: NCT02817048 Not yet recruiting - Clinical trials for Solitary Pulmonary Nodule

Tubeless VATS for Peripheral Lung Nodule

Start date: June 2016
Phase: N/A
Study type: Interventional

Chest tube placement after thoracoscopy surgery had been generally accepted as routine procedure for removal of the residual intrapleural fluid and air, however, it would cause post-operative pain, prohibit ambulation after surgery, and prolong the hospital stay. According to the recent studies, omission of chest tube placement after minor thoracoscopic procedures (such as pulmonary wedge resection) had been safe and feasible, and it also reduced the post-operative pain and shortened the hospital stay. We will conduct a prospective randomized trial in National Taiwan University Hospital.

NCT ID: NCT02773992 Recruiting - Clinical trials for Solitary Pulmonary Nodule

Clinical Study of Three Plus Two Type Early Diagnosis of Pulmonary Nodules in Medical Internet of Things

Start date: August 2015
Phase: N/A
Study type: Observational

Medical The Internet of Things (IoT), a recent breakthrough in communication technology, could be helpful in improving health care delivery and saving medical costs, but regarding pulmonary nodule management it is still at the basic understanding. Investigators adopt "Internet of things medical three plus two type pulmonary nodule diagnosis" which chun-xue Bai put forward, used a developed a mobile phone-based IoT (mIoT) platform and initiated a randomized, multicenter, controlled trial to value clinical effectivity of "Internet of things medical three plus two type pulmonary nodule diagnosis" in the management of pulmonary nodules. In this study, at least 600 patients with pulmonary nodules (no typical symptoms, often single, clear boundary, increased density, soft tissue shadow surrounded by lung parenchyma with diameter ≤3 cm) will be randomly allocated to the control group, which receives routine follow-up, or the intervention group, which receives "Internet of things medical three plus two type pulmonary nodule diagnosis" management. Endpoints of the study include: (1) The positive diagnosis rate of lung cancer in I stage; (2) 5 year disease-free survival rate and overall survival rate; (3) direct medical costs per year. Results from this study should provide direct evidence for the suitability of "Internet of things medical three plus two type pulmonary nodule diagnosis" in pulmonary nodules patients management.

NCT ID: NCT02726633 Recruiting - Clinical trials for Solitary Pulmonary Nodule

Evaluate the Utility of the ProLung China Test in the Diagnosis of Lung Cancer

ProLung
Start date: May 2015
Phase: N/A
Study type: Observational

A Study to evaluate the utility of the ProLung China Test as an adjunct to CT scan in the diagnosis of lung cancer.

NCT ID: NCT02693496 Recruiting - Clinical trials for Solitary Pulmonary Nodule

Mobile Lung Nodule Observatory for Worldwide, Evidenced-based Research

mLOWER
Start date: October 2015
Phase:
Study type: Observational

Patients with lung nodules may develop a variety of potentially severe symptoms. These symptoms may impact a patient's quality of life and lead to difficult treatment. Through this research program, the investigators want to understand the pathogenesis of the changes of these symptoms.

NCT ID: NCT02653859 Not yet recruiting - Clinical trials for Solitary Pulmonary Nodule

Evaluate the Auxiliary Diagnostic Value of Circulating Tumor Cells in Benign and Malignant Lung Nodules

Start date: January 2016
Phase: N/A
Study type: Observational

By testing the CTC number of new solitary pulmonary nodule patient, evaluating the correlation of CTC number and benign and malignant lung nodules auxiliary diagnosis, the correlation of CTC number and the size of lung nodules of the malignant patients, the correlation between the CTC number and subtypes of malignant lung nodules patients.The CTC and tumor markers will be detected before the patient received treatment. Tumor markers include Pro-GRP, NSE, CEA, CYFRA211, SCC.

NCT ID: NCT02623712 Active, not recruiting - Clinical trials for Carcinoma, Non-small-cell Lung

The Watch the Spot Trial

WTS
Start date: March 6, 2017
Phase: N/A
Study type: Interventional

This study will compare two clinically accepted protocols for surveillance imaging in individuals who are found to have a small pulmonary nodule on chest computed tomography (CT) scans.

NCT ID: NCT02531646 Enrolling by invitation - Clinical trials for Solitary Pulmonary Nodules

Clinical Evaluation of CARESTREAM Dual Energy and Digital Tomosynthesis

Start date: November 2015
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the imaging performance of Dual Energy and Digital Tomosynthesis (DE-DT) application against the commercially available predicate devices.

NCT ID: NCT02490059 Completed - Lung Cancer Clinical Trials

Ultrathin Bronchoscopy for Solitary Pulmonary Nodules

Babyscope
Start date: November 2000
Phase: Phase 4
Study type: Interventional

The evaluation of solitary pulmonary nodules (SPN) requires a balance between procedure-related morbidity and diagnostic yield, particularly in areas where tuberculosis is endemic. Data on ultrathin bronchoscopy (UB) for this purpose is limited. In this prospective randomised trial we compared diagnostic yield and adverse events of UB with standard-size bronchoscopy (SB) in a cohort of patients with SPN located beyond the visible range of SB.

NCT ID: NCT02448225 Completed - Lung Carcinoma Clinical Trials

18F-FSPG PET/CT in Imaging Patients With Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules

Start date: June 16, 2015
Phase: Phase 2
Study type: Interventional

This clinical trial compares fluorine F 18 L-glutamate derivative BAY94-9392 (18F-FSPG) positron emission tomography (PET)/computed tomography (CT) to the standard of care fluorodeoxyglucose F-18 (18F-FDG) PET/CT in imaging patients with newly diagnosed lung cancer or indeterminate pulmonary nodules. PET/CT uses a radioactive glutamate (one of the common building blocks of protein) called 18F-FSPG which may be able to recognize differences between tumor and healthy tissue. Since tumor cells are growing, they need to make protein, and other building blocks, for cell growth that are made from glutamate and other molecules. PET/CT using a radioactive glutamate may be a more effective method of diagnosing lung cancer than the standard PET/CT using a radioactive glucose (sugar), such as 18F-FDG.