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Clinical Trial Summary

This study was designed as a single-center, open, non-randomized trial.


Clinical Trial Description

In this study, patients with locally advanced or metastatic solid tumors were enrolled for a tolerance test and a pharmacokinetic study. The dosage increment principle of 3+3 was adopted. At the end of the tolerance test, 3 dose groups (low, medium and high) were selected to conduct pharmacokinetic studies after evaluation by the researchers on the premise of good safety, and at least 8 patients were included in each group for PK study (at least 8 patients in each group could be evaluated for PK ). After the end of the experimental drug tolerance and pharmacokinetics study, the safety and pharmacokinetics of single dose administration were compared with that of sodium norcantharidate for injection in the dose range of clinical use. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04673396
Study type Interventional
Source Beijing Nuokangda Pharmaceutical Technology Co., Ltd.
Contact Yunpeng Liu, Ph.D
Phone 13898865122
Email cmu_trial@163.com
Status Recruiting
Phase Phase 1
Start date September 22, 2020
Completion date July 1, 2022

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