First In Human Study of CX-801 in Advanced Solid Tumors

Status Not yet recruiting

Clinical Trial Summary

The purpose of this first-in-human study, CTMX-801-101, is to characterize the safety, tolerability, and antitumor activity of CX-801 as monotherapy and in combination with pembrolizumab in adult participants with advanced solid tumors.

Clinical Trial Description

The study is comprised of 2 parts. Part 1 involves CX-801 dose escalation to identify the maximum tolerated dose (MTD) of CX-801 as monotherapy and as combination therapy (CX-801 combined with pembrolizumab). Part 2 (dose expansion) will further assess safety and tolerability as well as preliminarily assess antitumor activity of CX-801 combination therapy in indication-specific expansion cohorts. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06462794
Study type	Interventional
Source	CytomX Therapeutics
Contact	Karen Deane
Phone	650-515-3185
Email	clinicaltrials@cytomx.com
Status	Not yet recruiting
Phase	Phase 1
Start date	June 30, 2024
Completion date	June 30, 2029

View Details

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