Sequential Neoadjuvant Chemotherapy in Soft Tissue Sarcoma

Status Recruiting

Clinical Trial Summary

Nearly half of patients with high-grade, localized soft tissue sarcoma (STS) of extremities and trunk wall develop disease recurrence after local therapy. Adjuvant chemotherapy with ifosfamide and doxorubicin may improve long-term disease-free survival, but the benefit of adjuvant treatment is limited and predictive factors for treatment response are lacking. The aim of this study is to explore sequential treatment with ifosfamide and doxorubicin in a neoadjuvant setting and to investigate biomarkers predictive of treatment response.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04776525
Study type	Interventional
Source	Oslo University Hospital
Contact	Kjetil Boye, MD PhD
Phone	+4722934000
Email	kjetil.boye@ous-hf.no
Status	Recruiting
Phase	Phase 2
Start date	April 27, 2021
Completion date	September 2036

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See also
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