Toripalimab Combined With CAV/IE Regimen

Status Recruiting

Clinical Trial Summary

The aim of this study was to investigate the efficacy and safety of CAV/IE chemotherapy combined with toripalimab versus CAV/IE chemotherapy alone in the treatment of patients with advanced or unresectable bone and soft tissue sarcomas who failed in standard treatment.

Clinical Trial Description

At present, there are many clinical trials of chemotherapy drugs combined with anti-PD-1 antibody in the treatment of tumor, but the clinical study of CAV/IE chemotherapy combined with anti-PD-1 antibody in the treatment of advanced or non resectable bone and soft tissue sarcoma has not been started, and the related research is still in the blank state. In view of the above problems, to observe and evaluate the efficacy and safety of CAV/IE chemotherapy combined with toripalimab versus CAV/IE chemotherapy alone in the treatment of advanced or non resectable bone and soft tissue sarcoma patients, so as to provide more treatment options for patients with advanced or non resectable bone and soft tissue sarcoma. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04589741
Study type	Interventional
Source	Sun Yat-sen University
Contact	Xing Zhang
Phone	02087343383
Email	zhangxing@sysucc.org.cn
Status	Recruiting
Phase	Phase 2
Start date	October 23, 2020
Completion date	June 30, 2026

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