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Clinical Trial Summary

Alveolar ridge preservation following tooth extraction has the ability to maintain the ridge dimensions and allow the implant placement in an ideal position fulfilling both functional and aesthetic results. Postextraction socket healing commonly results in resorption of the alveolar ridge.

To prevent this clinical situation, different authors have described several surgical procedures, ranging from regenerative techniques for socket preservation to immediate implant placement. Regenerative techniques have been widely tested in controlled and uncontrolled studies with various materials and clinical approaches: bone grafting alone, including autografts, allografts, xenografts, and alloplasts; membrane alone, whether absorbable or not; and membrane in conjunction with grafting.


Clinical Trial Description

Various classic studies in the 1960s showed that the resorption process of the postextraction alveolus in both jaws was significantly more pronounced on the buccal aspect. This comes as no surprise, as the buccal surface of the anterior alveolar ridge is commonly thin and fragile. The maxilla tends to exhibit greater reductions in width than in height. The loss of tissue contour takes place mostly during the first 1 to 3 months following tooth extraction. Because the healing patterns of human sockets are unpredictable architecture), then such common procedures as extractions may lead to intraoral situations in which the remaining healed ridge does not allow for an esthetic and functional solution without the aid of significant bone grafting. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03677479
Study type Interventional
Source Cairo University
Contact Ghada Adayil, Msc
Phone (+202)01006010412
Email ghada.adayil@dentistry.cu.edu.eg
Status Not yet recruiting
Phase Early Phase 1
Start date March 2019
Completion date August 2020

See also
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Completed NCT02444052 - Evaluation of Zimmer Puros® Allograft vs. Creos™ Allograft for Alveolar Ridge Preservation N/A
Recruiting NCT04377178 - Tooth Graft of Two Different Particle Sizes in Extraction Sockets N/A
Not yet recruiting NCT05838651 - Socket Preservation With BioHorizon's Striate+ Membrane and MinerOss X Plug N/A
Completed NCT03228771 - Socket Augmentation Using Atorvastatin With Or Without PRGF (Clinical and Histomorphometric Study) Phase 4
Recruiting NCT06429540 - Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus Xenograft N/A
Not yet recruiting NCT03573193 - Radiographic Changes Following Socket Preservation in Molars Using Bovine Bone Versus Using Beta Tri ca.ph N/A
Completed NCT05255341 - Clinical and Radiographic of the Effect of Socket Preservation Using the Roll Pedicle Connective Tissue Graft With Bovine Bone: A Case Series Trial. N/A
Recruiting NCT06275490 - Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus L- PRF Block N/A
Not yet recruiting NCT04197895 - Clinical and Radiographic Evaluation of Advanced Platelet Rich Fibrin in the Preservation of Alveolar Ridge Following Atraumatic Tooth Extraction N/A
Recruiting NCT03548896 - Ridge Regeneration in Three Wall Sockets N/A
Recruiting NCT06318650 - Post Extraction Changes After Ridge Preservation Using Allogeneic Dentin Matrix Vs Demineralized Freeze Dried Allograft N/A
Active, not recruiting NCT06251960 - Demineralized Dentin Graft in Preservation of Post-Extraction Sites Associated With Delayed Implant Placement N/A
Recruiting NCT05613075 - Effect of Locally Applied Hyaluronic Acid, Mixed With Autogenous Demineralized Tooth Graft, for Socket Preservation, Versus Autogenous De-mineralized Tooth Graft. N/A
Recruiting NCT04013425 - Socket Preservation Using the Ice Cream Cone Technique Versus Spontaneous Healing in Fresh Extraction Sockets. N/A