Clinical Trials Logo
  1. Home
  2. Social Isolation
  3. NCT05319301

Identification and Clinical Relevance of an Oxytocin Deficient State (Melatonin Study)

Social Isolation Clinical Trial

Official title:
Identification and Clinical Relevance of an Oxytocin Deficient State Following Melatonin Administration in Patients With Hypopituitarism: a Proof-of-concept, Physiopathological Study With a Control Group

Clinical Trial Summary

Oxytocin (OT) is a hypothalamic peptide that enters the peripheral circulation via the posterior pituitary gland. OT plays a key role in regulating appetite, psychopathology, prosocial behavior and sexual function. Hypopituitarism is associated with increased obesity, increased psychopathology, sexual and prosocial dysfunction despite appropriate hormone replacement. A few studies suggest the existence of a possible OT deficient state in hypopituitarism. In animal models, melatonin has shown to increase OT release. This study is designed to evaluate oxytocin values after administration of melatonin in adults (healthy volunteers and patients with hypopituitarism). The investigators hypothesize that OT response will be blunted following melatonin in patients with hypopituitarism compared to healthy controls.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05319301
Study type Interventional
Source Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Contact
Status Completed
Phase N/A
Start date April 1, 2022
Completion date November 1, 2023
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05831475 - LEAPTogether: An Intergenerational Intervention to Address Loneliness and Social Isolation N/A
Completed NCT03291717 - Bridging Community Gaps Photovoice N/A
Recruiting NCT06175299 - Social Functions to Promote Home-based Cognitive Training N/A
Completed NCT04573972 - Using Social Connectedness to Increase Physical Activity N/A
Not yet recruiting NCT05031247 - Refugee Mental Health and Wellness Pilot Study N/A
Completed NCT02596672 - Promoting Walking in Older Adults Living in Independent Living Communities in Northern Ireland: A Feasibility Study. N/A
Active, not recruiting NCT05678985 - Evaluating Impact and Implementation of Choose to Move (Phase 4) N/A
Active, not recruiting NCT04072185 - PHYSICAL ACTIVITY AS A MEASURE OF IMPROVING THE EMOTIONAL STATE AND SOCIALIZATION IN THE ELDERLY N/A
Completed NCT06018974 - Digital Gaming Intervention for Older People in Long-term Care N/A
Recruiting NCT04897802 - Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study) Phase 4
Recruiting NCT06138301 - Telepsychiatry for Social Isolation in Youths N/A
Enrolling by invitation NCT06434298 - Provincial Scale-up of Choose to Move (CTM) Phase 4 N/A
Recruiting NCT05520450 - Telematic Support Group in Patients With Feelings of Loneliness and Social Isolation
Recruiting NCT05019053 - Acceptability/Feasibility of COVID-19 Intervention N/A
Completed NCT04567940 - ENRED@TE. Social Support in Southern Spain. Interventional Study N/A
Completed NCT04281654 - Effects of Arts Engagement on Physical Performance, Cognition, Social Isolation, and Self-Perception in Older Adults N/A
Completed NCT03472729 - AGE-ON 2.0: Expanding and Evaluating a Tablet Training Program for Older Adults N/A
Completed NCT03293823 - HARP-Project 1 Cognitive Training N/A
Completed NCT02835989 - Community Paramedicine at Home N/A
Completed NCT02041585 - Discharge Functional Status and Rehospitalization in the Elderly