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Social Anxiety Disorder clinical trials

View clinical trials related to Social Anxiety Disorder.

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NCT ID: NCT04979676 Completed - Clinical trials for Social Anxiety Disorder

Changing the Course of Social Anxiety in Adolescence

TeenSAD
Start date: March 15, 2019
Phase: N/A
Study type: Interventional

Social anxiety often reaches its peak during adolescence and may hold a noteworthy impact both at the social and academic levels. Though some adolescents easily learn to adequately cope with it, others become overwhelmed by social fears and end up avoiding social events or facing them with intense suffering. Adolescents with social anxiety disorder (SAD) seldom seek professional help and often become adults with SAD, making it necessary to timely intervene during early stages of the disorder and determine what works better, why, and for whom when trying to change the course of social anxiety in adolescence. Cognitive therapy (CT) has been the treatment of choice for adult SAD, but research within adolescent samples is scarce. More recently, third-wave cognitive approaches, namely compassion-focused therapy (CFT) and acceptance and commitment therapy (ACT), have also proven effective in treating mental disorders, but their efficacy towards adolescents' SAD remains unclear. This research project intended to evaluate and compare the therapeutic efficacy of CT, CFT, and ACT as applied to adolescents with SAD, in comparison with waiting-listed, after intervention and over a 12-weeks and a 24-weeks follow-up, using a randomized parallel trial approach. This methodology will allow to test if intervened subjects diverge from the non-intervened SAD subjects, and if therapeutic change differs across intervention conditions. Therapeutic change process will be investigated, specifically if efficacy is mediated by change in the core constructs of each theoretical framework. Finally, moderators of change such the initial level of symptomology will be examined, as to determine which intervention works best for whom. The same procedures will be repeated for each intervention condition, namely recruitment, intervention, and assessment. This research will provide evidence on which form of therapy may be the optimal choice in to intervene in SAD in general, and when dealing with diverse specific vulnerabilities associated with social fears. It will also add to the field of empirically validated therapies, with a specific focus on adolescence. From a societal perspective, the project will assist in empowering schools to contribute to shape how their students act and develop into socially apt adults.

NCT ID: NCT04782102 Completed - Clinical trials for Social Anxiety Disorder

SOPHIE: Online-intervention for Prevention and Treatment of Social Anxiety in Adolescents

SOPHIE
Start date: June 7, 2021
Phase: N/A
Study type: Interventional

This study's aim is to investigate the efficacy of the online-intervention SOPHIE. SOPHIE is an online-intervention for adolescents with social anxiety. In Switzerland, Germany, Austria and Liechtenstein, about one in 15 adolescents suffers from social anxiety. The SOPHIE intervention aims to help these adolescents to better understand and cope with their social anxiety symptoms and to feel more comfortable in social situations. The investigators intend to include 248 adolescents in the study. Stratified by subclinical and clinical level of social anxiety, participants will be randomly assigned to the SOPHIE group or the control group receiving care-as-usual. Both groups will complete online questionnaires and will be interviewed via telephone several times during the study. This allows to compare the two groups regarding their efficacy of the SOPHIE programme in terms of changes in social anxiety over time.

NCT ID: NCT04754802 Completed - Clinical trials for Social Anxiety Disorder

PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge

Palisade-1
Start date: May 24, 2021
Phase: Phase 3
Study type: Interventional

This Phase 3 clinical trial is designed to evaluate the efficacy, safety, and tolerability of the acute administration of 3.2 µg of PH94B to relieve symptoms of anxiety in adult subjects with social anxiety disorder (SAD) during an induced public speaking challenge. Subject participation in the Study will last a total of 3 to 7 weeks, depending on the duration of the screening period and intervals between visits. Upon signing an informed consent, all subjects will complete Visit 1 (Screening) and enter a screening period lasting between 3 and 35 days. If subjects meet all eligibility criteria at the end of the screening period, subjects will return for Visit 2 and self-administer the nasal spray and then participate in a 5 minute public speaking challenge. During the public speaking challenge, the subject will be asked for their anxiety score, which will be recorded by a trained observer. At Visit 3, the subjects will undergo the same public speaking procedure once again as they did in Visit 2. One week after the completion of the Visit 3 public speaking challenge, the subject will come back for Visit 4 (Follow-up) that will involve a repeat of the safety and psychiatric assessments conducted at Screening.

NCT ID: NCT04729803 Completed - Clinical trials for Social Anxiety Disorder

Attention, Teleconferencing and Social Anxiety

Start date: January 18, 2021
Phase: N/A
Study type: Interventional

This study involves completing some online assessments and an intervention for social anxiety that all involve interactions with other people on a teleconferencing call.

NCT ID: NCT04179526 Completed - Clinical trials for Major Depressive Disorder

Transdiagnostic Internet-delivered REBT Intervention for Adolescents' Internalizing Problems

REBTonAd
Start date: January 25, 2020
Phase: N/A
Study type: Interventional

To investigate the efficacy and mechanisms of change of an Internet-delivered transdiagnostic REBT intervention for adolescents with internalizing problems.

NCT ID: NCT04111874 Completed - Clinical trials for Autism Spectrum Disorder

Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD

Start date: July 30, 2019
Phase: N/A
Study type: Interventional

This study implements an anxiety-focused, parent-led, therapist-assisted cognitive behavioral teletherapy for parents of youth with ASD and anxiety.

NCT ID: NCT03925987 Completed - Clinical trials for Generalized Anxiety Disorder

Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide

Start date: June 7, 2018
Phase: N/A
Study type: Interventional

Anxiety disorders affect over a quarter of the population, yet very little is known about the variables that predict treatment outcome. The planned study explores whether a patient's response to a physiological test involving inhalation of carbon dioxide predicts their response to exposure therapy.

NCT ID: NCT03785223 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

A 14 Week, Randomized, Placebo-Controlled Cross-Over Study of Methylphenidate Hydrochloride Controlled Release Capsules in Adult ADHD With and Without Anxiety Disorder Comorbidity

Start date: April 20, 2019
Phase: Phase 4
Study type: Interventional

Other psychiatric disorders, including anxiety, often co-occur with adult ADHD; with 85% of ADHD patients having at least one other psychiatric condition. The presence of a co-occurring anxiety disorder has been associated with additive clinical effects, leading to more global impairment, poorer outcome, greater resistance to treatment and increased costs of illness. Stimulants are effective first-line treatments for adult ADHD patients, however the literature has mostly examined these treatments in pure ADHD populations (i.e. without other psychiatric disorders). Thus, there is little information to guide physicians in making treatment decisions for patients with ADHD and a co-occurring condition. This trial aims to evaluate the efficacy and safety of methylphenidate hydrochloride controlled release capsules (Foquest) in treating adults aged 18-65 years with DSM-5 ADHD with and without a co-occurring anxiety disorder.The study uses a 14-week, randomized, placebo-controlled, cross-over design.

NCT ID: NCT03720795 Completed - Clinical trials for Autism Spectrum Disorder

Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and Anxiety

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

This study implements a parent-led, flexible, individually-tailored cognitive-behavioral intervention for children with ASD and anxiety.

NCT ID: NCT03709615 Completed - Clinical trials for Social Anxiety Disorder

Therapeutic Processes in iCBT for SAD

Start date: December 20, 2017
Phase: N/A
Study type: Interventional

The current study examines therapeutic processes during internet-based cognitive-behavioral therapy for social anxiety disorder. Participants will be randomized to either treatment or wait-list conditions. Participants in the wait-list condition will receive active treatment following the wait-list period.