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NCT ID: NCT06055972 Recruiting - Clinical trials for Coronary Artery Disease

Impact of Patient-Centered Approach for Communicating Coronary Calcium on Cardiovascular Health

Start date: December 19, 2023
Phase: N/A
Study type: Interventional

This multicenter clustered randomized prospective study will be managed by the American College of Radiology Center for Research and Innovation (ACR CRI). The research team aims to test the efficacy of a patient-centered educational intervention based on coronary artery calcification (CAC) information in cardiovascular risk factor modification of a cohort of patients enrolled in lung cancer screening (LCS) programs across the country.

NCT ID: NCT06055036 Recruiting - Obesity Clinical Trials

Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention

Start date: August 24, 2023
Phase: N/A
Study type: Interventional

Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8 (LE8; LS7+sleep) metrics, is a major contributor to Black men having the shortest life-expectancy of any non-indigenous race/sex group. Unfortunately, a paucity of literature exists on interventions aimed at improving CVH among Black men. The team of clinician scientists and community partners co-developed a community-based lifestyle intervention titled Black Impact: a 24-week intervention for Black men with less-than-ideal CVH (<4 LS7 metrics in the ideal range) with 45 minutes of weekly physical activity, 45 minutes of weekly health education, and engagement with a health coach, group fitness trainer, and community health worker. Single-arm pilot testing of the intervention (n=74) revealed high feasibility, acceptability, and retention and a 0.93 (95% confidence interval: 0.40, 1.46, p<0.001) point increase in LS7 score at 24 weeks. Secondary outcomes included improvements in psychosocial stress (i.e., perceived stress, depressive symptoms), patient activation, and social needs. Thus, robustly powered clinical trials are needed to determine the efficacy of Black Impact and to evaluate the underlying interpersonal and molecular pathways by which Black Impact improves psychosocial stress and CVH. Thus, the investigators propose a randomized, wait-list controlled trial of Black Impact. This novel, community-based intervention to provide a scalable model to improve CVH and psychosocial stress at the population level and evaluate the biological underpinnings by which the intervention mitigates cardiovascular disease risk. The proposed study aligns with American Heart Association's commitment to addressing CVH equity through innovative, multi-modal solutions.

NCT ID: NCT06051474 Recruiting - Smoking Cessation Clinical Trials

Treating Caregivers Who Smoke at AFCH

Start date: March 5, 2024
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to 1) see if a smoking cessation program is something that caregivers will use while their child is hospitalized, 2) see if caregivers think this program is something we should institute across the hospital, and 3) see if this program can help caregivers reduce their smoking. Participants will: - Complete a survey regarding smoking behavior and thoughts about quitting; - Undergo a 20-minute counseling session; and, - Use nicotine patches and mini-lozenges for 2 weeks

NCT ID: NCT05961813 Recruiting - Smoking Cessation Clinical Trials

Intervention for Smoking Cessation in Pre-Surgical Patients.

Start date: May 20, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to assess efficacy of an intensive pre-surgical intervention to quit smoking in smoking patients who will be operated on implant orthopedic surgery or general and urological surgery. The main question[s] it aims to answer are: - Evaluate the efficacy of intensive pre surgical intervention to quit smoking compared to a brief intervention - Evaluate the implementation of this protocol. Participants will be randomized to 2 intervention groups (patients programmed for protesic implant orthopedic surgery in the first group, and general and urological surgery) and 2 control groups (stratified in the same manner as the intervention groups), and will be monitored through telematic check ups via phone calls.

NCT ID: NCT05952401 Enrolling by invitation - Smoking Cessation Clinical Trials

Implementation Science to Reduce the Disparity in Tobacco Treatment Among Individuals With Serious Mental Illness

ISRAISE
Start date: May 31, 2024
Phase: N/A
Study type: Interventional

This is a pilot trial to examine the feasibility and preliminary effect of a multilevel intervention 'Nudges to Quit' on smoking cessation in patients with serious mental illness who smoke in a community mental health center (CMHC). "Nudges to Quit" is a multilevel intervention to increate engagement of patient, case worker, and pharmacist with tobacco treatment. The pilot trial is to generate the needed evidence for designing a future large trial to evaluate the effect of 'Nudges to Quit' as a multilevel intervention to increase tobacco treatment and reduce tobacco use among patients with serious mental illness.

NCT ID: NCT05936099 Recruiting - Smoking Clinical Trials

Adolescent Inpatient Tobacco and ENDS Intervention

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to develop and evaluate an evidence-based intervention to assist adolescents and young adults with current vaping to quit vaping and smoking.

NCT ID: NCT05920772 Recruiting - Smoking Clinical Trials

Process and Effect Evaluation of the KickAsh! Intervention

Start date: October 4, 2023
Phase: N/A
Study type: Interventional

The goal of this evaluation study is to evaluate the KickAsh! intervention, an intervention aiming to prevent smoking initiation in adolescents living in vulnerable socioeconomic situations. This intervention will be implemented in youth social work organisation that offer sport and/or recreational activities for these adolescents. Youth workers will act as implementers of the intervention. The main aim of this study is to evaluate the effect of the intervention, whether it does or does not produce change in the smoking initiation behaviour of adolescents (= effect evaluation). Secondly, the study aims to evaluate the implementation process to generate more understanding concerning why the intervention does or does not produces change. Therefore, it will be investigated how the intervention was implemented, what exactly was implemented, in which context the intervention was implemented... (= process evaluation) For the effect evaluation adolescents will be asked to fill in a questionaire at three time points. For the process evaluations interviews and focus groups will be organised with the adolescents and youth workers respectively. Two groups will participate to this study: one group existing of organisations where the intervention will be implemented (=intervention group), and one group where the intervention will not be implemented (= control group).

NCT ID: NCT05910203 Recruiting - Smoking Clinical Trials

The Effect of Education Based on Health Belief Model on Smoking Behaviors of Visually Impaired Individuals

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

Health is a main human right and a need for every human being. However, due to some congenital or acquired reasons, individuals may be disabled and cannot participate in social life at the same level as their normally developing peers. The gradual increase in the world population, the advances in the treatment of chronic diseases and the prolongation of life expectancy at birth, along with the increase in economic, social and psychological problems and deterioration in environmental conditions show that the number of disabled individuals will increase in the future. Diseases caused by the use of tobacco and tobacco products rank first among preventable diseases in the world, and tobacco use is a very important public health problem. Nurses use various models developed as a guide in developing goals for lifestyle change in individuals and in interventions to achieve this. One of the studies they conduct based on the models is smoking cessation. It is believed that the studies to be carried out will strengthen the perceptions of individuals about protecting and improving their health and will guide the way in which the obstacles to smoking cessation can be perceived and resolved more easily. Based on this, it is thought that the smoking cessation study to be carried out by using HBM in visually impaired individuals will draw attention to unhealthy lifestyle behaviors and smoking addiction, which is one of these behaviors. The study was designed experimentally with "pretest-posttest control group". Before and after the planned smoking cessation training given based on HBM, the scores of Fagerström Nicotine Dependence Test and the smoking cessation scale according to HBM and hemoglobin and CO measurement values of the visually impaired individuals will be compared. Statistical package program will be used for coding, statistical analysis and evaluation of the data to be obtained from the study. T-test will be used in independent groups and t-test in dependent groups depending on the distribution features of the data in the statistical analysis. The normality distribution of the data will be evaluated by Wilk's, Kurtosis and Skewness coefficients. In the data distributed normally, non-parametric tests, Kruskal Wallis test or Mann-Whitney test will be used, and parametric tests, dependent and independent groups' t-test in two variables and ANOVA (analysis of variance) will be used in two or more variables.

NCT ID: NCT05859451 Recruiting - Smoking Clinical Trials

Effect of Tobacco Heating System (THS) on Closed Tibia Fracture Healing

Start date: June 2, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to investigate the role of switching from cigarette smoking (CS) to tobacco heat system (THS) on the clinical outcome of closed tibia fractures from smokers' orthopedic patients. Validated and standardized assays, medical state and self-reported outcomes will be evaluated in orthopedic patients' smokers or switch from CS to using THS throughout six months compare to ex-smokers (control).

NCT ID: NCT05852860 Enrolling by invitation - HIV Clinical Trials

A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science Research

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The objective of this trial is to evaluate the effectiveness of "nudges" to clinicians, patients, or both in increasing referral to, and engagement with, tobacco use treatment services (TUTS) for HIV patients versus usual care. This will be a four-arm pragmatic cluster randomized clinical trial. The investigators hypothesize that each of the implementation strategy arms will significantly increase TUTS referral and engagement compared to usual care and that the combination of nudges to clinicians and to patients will be the most effective.