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Smoking Cessation clinical trials

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NCT ID: NCT03397511 Completed - Smoking Cessation Clinical Trials

Incorporating Financial Incentives to Increase Smoking Cessation Among Asian Americans Residing in New York City

Start date: September 5, 2018
Phase: N/A
Study type: Interventional

Financial incentives for motivating health change have been increasingly employed in various healthcare sectors. They can be a potentially effective approach to promote smoking behavioral change and increase the use of evidence-based counseling and pharmacotherapy. Smoking cessation randomized clinical trials (RCT) incorporating financial incentives have been conducted in different populations; however, there has not been a randomized clinical trial coupled with a financial incentive with Asian American cigarette smokers. The purpose of this pilot study is to examine the feasibility of implementing an incentivized smoking cessation program among Asian American smokers in New York City.

NCT ID: NCT03396029 Completed - Physical Activity Clinical Trials

Tailored Written Lifestyle Feedback in Colorectal Cancer Screening

Start date: November 1, 2014
Phase: N/A
Study type: Interventional

This randomized controlled trial aims to investigate the effect of an individually tailored lifestyle feedback letter and a leaflet on lifestyle in the context of sigmoidoscopy screening.

NCT ID: NCT03375840 Completed - Smoking Cessation Clinical Trials

Pictorial Warning Labels and Memory for Cigarette Health-risk Information Over Time

Start date: April 17, 2015
Phase: Phase 3
Study type: Interventional

Pictorial cigarette warning labels (PWLs) are thought to increase risk knowledge, but experimental research has not examined PWLs' longer term effects on memory for health risks. This trial tests memory for health risks immediately or after a six-week delay for US-representative adult smokers, US-representative teen smokers/vulnerable smokers, and Appalachian-representative adult smokers. In addition, the trial tests the effects of different warning label components and the consequences of memory for labels on risk perceptions and quit intentions.

NCT ID: NCT03362099 Completed - Smoking Cessation Clinical Trials

Efficacy of the Use of Genetic Markers in the Choice of the Pharmacological Treatment of Smoking (GENTSMOKING)

GENTSMOKING
Start date: November 1, 2016
Phase: Phase 4
Study type: Interventional

Smoking is the leading cause of avoidable death in the world. Smoking is associated with the development of cardiovascular and respiratory diseases, as well as being considered a leading cause of cancer death. Data show that smokers have increased cardiovascular risk in relation to former smokers, even in comparison with individuals who have had a long and intense history tobacco use. Considering this scenario, some drugs are used in tobacco cessation therapy. The first-line anti-smoking treatments approved by the Food and drug administration ( FDA ) are nicotinic reuptake therapy, bupropion ( norepinephrine and dopamine reuptake inhibitor) and varenicline ( partial agonist of nicotinic receptors composed of subunits alpha4Beta2 ). A metanalysis of 16 clinical studies indicated that smokers treated with bupropion had a higher abstinence rate compared to those receiving placebo - Odds ratio (OR ) - of 1,97 for treatment success. Varenicline is more effective compared to others smoking cessation drugs approved by the FDA, with an OR of 2,27 ( IC 95% 2,02-2,55 ) compared to placebo. However, Varenicline is much more expensive than bupropion. Significant advances in genetics have made the variability of the individual response to drugs, as far as efficacy as well as the rate of adverse effects, begin to be specifically investigated through pharmacogenetics studies.

NCT ID: NCT03346291 Completed - Schizophrenia Clinical Trials

Examining Persistence in Smokers With Schizophrenia

Start date: January 2017
Phase: N/A
Study type: Interventional

All participants will receive free weekly counseling (8- weeks) and free nicotine patches (10-weeks). They will complete assessment measures commonly used in smoking cessation studies. We hope to show that this treatment is feasible in this small pilot study before comparing it to a more established treatment in a future randomized clinical trial.

NCT ID: NCT03342027 Completed - HIV Clinical Trials

Smoking Cessation Interventions for People Living With HIV in Nairobi, Kenya

Start date: August 1, 2020
Phase: Phase 3
Study type: Interventional

The proposed study will use a factorial design to evaluate the most promising and accessible behavioral and pharmacologic treatments aimed at achieving maximal efficacy for smoking cessation among people living with HIV who smoke. The study will randomize 300 participants people living with HIV , who smoke and who are receiving care in HIV clinics affiliated with the Center for International Health, Education, and Biosecurity in Nairobi, Kenya to one of the following 4 conditions: (1) bupropion + Positively Smoke Free (an 8 session tailored behavioral intervention for people living with HIV smokers); (2) bupropion + Standard of Care (brief advice to quit); (3) Placebo + Positively Smoke Free; and (4) Placebo + Standard of Care.

NCT ID: NCT03316170 Completed - Smoking Cessation Clinical Trials

Consultation, Advice, and Tailored Support (CATS) for Cancer Survivors

Start date: November 6, 2017
Phase: Phase 2
Study type: Interventional

The objectives of this pilot clinical trial are: 1) To evaluate the feasibility and acceptability of a new approach to smoking cessation induction treatment in cancer survivors with low social resources, and 2) To assess the effectiveness of said treatment for key events in the process of smoking cessation.

NCT ID: NCT03295643 Completed - Smoking Cessation Clinical Trials

Outcomes From a Mobile Smoking Cessation Program During a Monitoring Period of 6 Months

Start date: October 4, 2017
Phase: N/A
Study type: Interventional

Prospective, open label, single center clinical study enrolling 260 subjects in a mobile smoking cessation program using a smartphone app and a handheld breath sensor with coaching support over a six month period.

NCT ID: NCT03295409 Completed - Smoking Cessation Clinical Trials

Testing Familial Self-affirmation for Smoking Cessation

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

Evidence suggests that affirming the self can help people to make changes in their health behavior. Typically, people affirm a personally-important value, but evidence suggests that affirming the values of family ("familial self-affirmation") might exert stronger effects. The aim of the present study is to examine the effects of familial self-affirmation versus standard self-affirmation versus a control group on smoking cessation.

NCT ID: NCT03291587 Completed - Smoking Cessation Clinical Trials

Implementation of Smoking Cessation Within NCI Community Oncology Research Program (NCORP) Sites

OaSiS
Start date: June 1, 2018
Phase: N/A
Study type: Interventional

Evaluate a multi-faceted training program to improve short-term smoking cessation rates (<14 days post-visit) and short (3 months) and sustained abstinence (6 months) among 1,114 enrolled smokers who present for low-dose computed tomography (LDCT) lung cancer screening in 26 community-based practices.